Background We previously demonstrated that neuregulin-1 (NRG-1) was neuroprotective in
rats following ischemic stroke. Neuroprotection by NRG-1 was associated with the …

Neuregulins are a family of growth factors with potent neuroprotective properties. We
recently demonstrated that neuregulin-1 blocked delayed neuronal death following focal …

The purpose of this study was to investigate the therapeutic efficacy and mechanism of
recombinant human NRG-1 to attenuate ischemia/reperfusion brain injury. NRG-1 (3.0 …

Abstract Background Neuregulin-1 (NRG-1) has been shown to act as a neuroprotectant in
animal models of nerve agent intoxication and other acute brain injuries. We recently …

Neuregulin-1 (NRG-1) is expressed throughout the immature and adult central nervous
system and it has been demonstrated to influence the migration of a variety of cell types in …

Identifying novel neuroprotectants that can halt or reverse the neurological effects of stroke
is of interest to both clinicians and scientists. We and others previously showed the pre …

Cerebellum undergoes degenerative changes in neurodegenerative diseases. Two main
factors including oxidative stress and neuroinflammation mediate neurodegeneration …

Neuregulin-1 (NRG-1) is a member of the epidermal growth factor family. Our previous study
showed that NRG-1 protected neurons from apoptosis following focal cerebral ischemia by …

Neuroinflammation contributes to the pathophysiology of diverse diseases including stroke,
traumatic brain injury, Alzheimer's disease, Parkinson's disease, and multiple sclerosis …

Neuregulin-1 (NRG-1) is a growth factor with potent neuroprotective capacity in ischemic
stroke. We recently showed that NRG-1 reduced neuronal death following transient middle …