Abstract Purpose Pituitary neuroendocrine tumors (PitNETs) are frequent intracranial
neoplasms that present heterogenic characteristics. Little is known about the immune cell …

Purpose Tumor immune microenvironment in pituitary neuroendocrine tumors (PitNETs) and
application of current immunotherapy for refractory PitNETs remains debated. We aim to …

Macrophages are one of the most common infiltrating immune cells and an essential
component of tumor microenvironment. Macrophages and the soluble cytokines and …

Most pituitary adenomas (PAs) are considered benign tumors, but approximately 0.2% can
present metastasis and are classified as pituitary carcinomas (PCs). Refractory PAs lie …

The pituitary tumour microenvironment encompasses a spectrum of non-tumoural cells, such
as immune, stromal or endothelial cells, as well as enzymes and signalling peptides like …

Object: This study aimed to explore the relationship between the aggressiveness and
immune cell infiltration in pituitary adenoma (PA) and to provide the basis for immuno …

Tumor immune microenvironment has been gradually recognized as a key contributor to
tumor development, progression, and control. Immune cell infiltrates in brain tumors have …

Non-tumoural cells within the tumour microenvironment (TME) influence tumour
proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary …

Purposes Immunotherapies for solid tumor are gaining traction in the clinic, however, the
immunological landscape of pituitary adenomas (PAs) is not well defined. In the present …

The microenvironment of pituitary adenomas (PAs) includes a range of non-tumoral cells,
such as immune and stromal cells, as well as cell signaling molecules such as cytokines …