Hyperglycemia in early postnatal life of preterm infants with incompletely vascularized
retinas is associated with increased risk of potentially blinding neovascular retinopathy of …

Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of
prematurity, diabetic retinopathy, and age-related macular degeneration. Using a mouse …

The neural cells and factors determining normal vascular growth are not well defined even
though vision‐threatening neovessel growth, a major cause of blindness in retinopathy of …

Retinopathy of prematurity (ROP) is a blinding disease, initiated by delayed retinal vascular
growth after premature birth. There are both oxygen‐regulated and non‐oxygen‐regulated …

Background: Retinopathy of prematurity (ROP) continues to be a major cause of blindness in
children. Although ablation of the retina reduces the incidence of blindness by suppressing …

Retinopathy of prematurity (ROP) is a common blinding disease in children in the developed
world despite current treatment, and is becoming increasingly prevalent in the developing …

Background: Current treatments for retinopathy of prematurity (ROP) targeting single
vascular growth factors are ineffective in preventing neoangiogenesis. Methods: We …

Purpose.: Fibroblast growth factor (FGF) 2 is a potent endothelial cell mitogen and survival
factor that is postulated to participate in the pathogenesis of retinopathy of prematurity …

At preterm birth, the retina is incompletely vascularized. Retinopathy of prematurity (ROP) is
initiated by the postnatal suppression of physiological retinal vascular development that …

Oxygen administration to immature neonates suppresses VEGF-A expression in the retina,
resulting in the catastrophic vessel loss that initiates retinopathy of prematurity. To …