Emerging targets in type 2 diabetes and diabetic complications
S Demir, PP Nawroth, S Herzig… - Advanced …, 2021 - Wiley Online Library
Type 2 diabetes is a metabolic, chronic disorder characterized by insulin resistance and
elevated blood glucose levels. Although a large drug portfolio exists to keep the blood …
elevated blood glucose levels. Although a large drug portfolio exists to keep the blood …
Diabetes and complications: cellular signaling pathways, current understanding and targeted therapies
KA Adeshara, AG Diwan, RS Tupe - Current drug targets, 2016 - ingentaconnect.com
Diabetes is a metabolic disorder and over the past decades, it has become a major cause of
morbidity and mortality affecting the youth and middle-aged as it is the fourth leading cause …
morbidity and mortality affecting the youth and middle-aged as it is the fourth leading cause …
[HTML][HTML] Advances in research on type 2 diabetes mellitus targets and therapeutic agents
J Su, Y Luo, S Hu, L Tang, S Ouyang - International Journal of Molecular …, 2023 - mdpi.com
Diabetes mellitus is a chronic multifaceted disease with multiple potential complications, the
treatment of which can only delay and prolong the terminal stage of the disease, ie, type 2 …
treatment of which can only delay and prolong the terminal stage of the disease, ie, type 2 …
Mechanisms by which diabetes increases cardiovascular disease
CA Gleissner, E Galkina, JL Nadler, K Ley - Drug Discovery Today …, 2007 - Elsevier
Diabetes mellitus is one of the major risk factors for cardiovascular disease which is the
leading cause of death in the United States. Increasing prevalence of diabetes and diabetic …
leading cause of death in the United States. Increasing prevalence of diabetes and diabetic …
[HTML][HTML] Deconstructing type 2 diabetes
SI Taylor - Cell, 1999 - cell.com
Diabetes mellitus is a major public health problem, affecting∼ 5% of the population. The
chronic complications of diabetes cause enormous human suffering in the form of blindness …
chronic complications of diabetes cause enormous human suffering in the form of blindness …
[HTML][HTML] Insulin resistance, type 1 and type 2 diabetes, and related complications 2017
JF Ndisang, A Vannacci, S Rastogi - Journal of diabetes research, 2017 - ncbi.nlm.nih.gov
The global escalation of obesity and diabetes in developed and developing nations poses a
great health challenge. Obesity is one of the major causes of type 2 diabetes. Type 1 …
great health challenge. Obesity is one of the major causes of type 2 diabetes. Type 1 …
Mechanistic insights into diabetes mellitus and oxidative stress
K Maiese, ZZ Chong, YC Shang - Current medicinal chemistry, 2007 - ingentaconnect.com
Diabetes mellitus (DM) is a significant healthcare concern worldwide that affects more than
165 million individuals leading to cardiovascular disease, nephropathy, retinopathy, and …
165 million individuals leading to cardiovascular disease, nephropathy, retinopathy, and …
Molecular targets of diabetic cardiovascular complications
FK Ahmad, Z He, GL King - Current drug targets, 2005 - ingentaconnect.com
Both the macro-and microvascular complications adversely affect the life quality of patients
with diabetes and have been the leading cause of mortality and morbidity in this population …
with diabetes and have been the leading cause of mortality and morbidity in this population …
Mechanisms of diabetic complications
It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …
required, but also for its major complications, affecting both small and large blood vessels …
[PDF][PDF] Therapeutic targets for diabetes mellitus: an update
Diabetes mellitus is a common form of metabolic disorder where level of blood glucose in
the bloodstream raises high, because of deficiency of insulin and development of insulin …
the bloodstream raises high, because of deficiency of insulin and development of insulin …