Inflammation in Parkinson's disease: mechanisms and therapeutic implications

M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Parkinson's disease and enhanced inflammatory response

I Stojkovska, BM Wagner… - … biology and medicine, 2015 - journals.sagepub.com
Parkinson's disease (PD) is the first and second most prevalent motor and
neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of …

Neuroinflammation in Parkinson's disease and its potential as therapeutic target

Q Wang, Y Liu, J Zhou - Translational neurodegeneration, 2015 - Springer
Abstract Parkinson's disease (PD), the second most common age-associated
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and …

Neuroinflammation in Parkinson's disease: role in neurodegeneration and tissue repair

S Vivekanantham, S Shah, R Dewji… - International Journal …, 2015 - Taylor & Francis
Neuroinflammation in Parkinson's disease [PD] is a process that occurs alongside the loss of
dopaminergic neurons, and is associated with alterations to many cell types, most notably …

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy

L Qian, PM Flood, JS Hong - Journal of neural transmission, 2010 - Springer
Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …

Neuroinflammation and Parkinson's disease—from neurodegeneration to therapeutic opportunities

B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …

The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: focus on astrocytes

R Niranjan - Molecular neurobiology, 2014 - Springer
Neuroinflammation plays a key role in the pathogenesis of Parkinson's disease (PD).
Epidemiologic, animal, human, and therapeutic studies support the role of oxidative stress …

The role of neuroinflammation on the pathogenesis of Parkinson's disease

YC Chung, HW Ko, EG Bok, ES Park, SH Huh… - BMB …, 2010 - koreascience.kr
Parkinson's Disease (PD) is a common neurodegenerative disease characterized by the
progressive degeneration of nigrostriatal dopaminergic (DA) neurons. Although the …

Cellular and molecular mediators of neuroinflammation in the pathogenesis of Parkinson's disease

SV More, H Kumar, IS Kim, SY Song… - Mediators of …, 2013 - Wiley Online Library
Neuroinflammation is a host‐defense mechanism associated with restoration of normal
structure and function of the brain and neutralization of an insult. Increasing …

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …