[HTML][HTML] LINE-1 retrotransposons contribute to mouse PV interneuron development
GO Bodea, JM Botto, ME Ferreiro… - Nature …, 2024 - nature.com
Retrotransposons are mobile DNA sequences duplicated via transcription and reverse
transcription of an RNA intermediate. Cis-regulatory elements encoded by retrotransposons …
transcription of an RNA intermediate. Cis-regulatory elements encoded by retrotransposons …
L1 retrotransposition in neurons is modulated by MeCP2
Long interspersed nuclear elements-1 (LINE-1 or L1s) are abundant retrotransposons that
comprise approximately 20% of mammalian genomes,,. Active L1 retrotransposons can …
comprise approximately 20% of mammalian genomes,,. Active L1 retrotransposons can …
Neuronal genome plasticity: retrotransposons, environment and disease
MJHC Kempen, GO Bodea, GJ Faulkner - Human retrotransposons in …, 2017 - Springer
The neuronal genome has long been considered as a stably persisting entity interpreted as
the foundation of neurobiology. Over the past decade, it has become increasingly clear that …
the foundation of neurobiology. Over the past decade, it has become increasingly clear that …
[PDF][PDF] LINE-1: creators of neuronal diversity
CA Thomas, AR Muotri - Frontiers in Bioscience-Elite, 2012 - article.imrpress.com
Long interspersed nucleotide element 1 (L1) is a family of non-LTR retrotransposons that
can replicate and reintegrate into the host genome. L1s have considerably influenced …
can replicate and reintegrate into the host genome. L1s have considerably influenced …
Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia
Retrotransposons can cause somatic genome variation in the human nervous system, which
is hypothesized to have relevance to brain development and neuropsychiatric disease …
is hypothesized to have relevance to brain development and neuropsychiatric disease …
L1 retrotransposons and somatic mosaicism in the brain
SR Richardson, S Morell… - Annual review of genetics, 2014 - annualreviews.org
Long interspersed element 1 (LINE-1 or L1) retrotransposons have generated one-third of
the human genome, and their ongoing mobility is a source of inter-and intraindividual …
the human genome, and their ongoing mobility is a source of inter-and intraindividual …
L1 retrotransposition in neural progenitor cells
AR Muotri - Transposons and Retrotransposons: Methods and …, 2016 - Springer
Long interspersed nucleotide element 1 (LINE-1 or L1) is a family of non-LTR
retrotransposons that can replicate and reintegrate into the host genome. L1s have …
retrotransposons that can replicate and reintegrate into the host genome. L1s have …
LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?
T Singer, MJ McConnell, MCN Marchetto… - Trends in …, 2010 - cell.com
LINE-1 (L1) elements are retrotransposons that insert extra copies of themselves throughout
the genome using a 'copy and paste'mechanism. L1s comprise nearly∼ 20% of the human …
the genome using a 'copy and paste'mechanism. L1s comprise nearly∼ 20% of the human …
Somatic retrotransposition in the developing rhesus macaque brain
V Billon, FJ Sanchez-Luque, J Rasmussen… - Genome …, 2022 - genome.cshlp.org
The retrotransposon LINE-1 (L1) is central to the recent evolutionary history of the human
genome and continues to drive genetic diversity and germline pathogenesis. However, the …
genome and continues to drive genetic diversity and germline pathogenesis. However, the …
Somatic retrotransposition alters the genetic landscape of the human brain
Retrotransposons are mobile genetic elements that use a germline 'copy-and-
paste'mechanism to spread throughout metazoan genomes. At least 50 per cent of the …
paste'mechanism to spread throughout metazoan genomes. At least 50 per cent of the …