Osteoarthritis (OA) is an age-related chronic degenerative joint disease where the main
characteristics include progressive degeneration of cartilage, varying degrees of synovitis …

Osteoarthritis (OA) is a common degenerative disease of the joints. It is primarily caused by
age, obesity, mechanical damage, genetics, and other factors, leading to cartilage …

Objectives Recent studies indicate that glucose metabolism is altered in rheumatoid arthritis
(RA) fibroblast-like synoviocytes (FLS). Hexokinases (HKs) catalyse the first step in glucose …

OBJECTIVE: HIF-1α and Runx2 expression usually increase in chondrocytes (CHs) during
osteoarthritis (OA), which involves the changes in glycolytic metabolism. However, the …

Introduction Abnormal glycolytic metabolism contributes to joint inflammation and
destruction in rheumatoid arthritis (RA). We examine the expression and function of …

Rheumatoid arthritis (RA) is a classic autoimmune disease characterized by uncontrolled
synovial proliferation, pannus formation, cartilage injury, and bone destruction. The specific …

Background Some studies have indicated that glucose metabolism plays an important role
in the pathogenesis of rheumatoid arthritis (RA). This study aimed to find the novel genes …

Context: Osteoarthritis (OA) is a common chronic degenerative joint disease resulting in
physical disability and reduced quality of life. Different biochemical signaling pathways are …

Glucose metabolism is considerably increased in inflamed joints of rheumatoid arthritis (RA)
patients at early stages. Fibroblast-like synoviocytes (FLSs) activation and subsequent joint …

Objective This study aimed to evaluate glycolysis inhibitor which can effectively ameliorate
arthritis by inhibiting synoviocyte activation through AMPK/NF-кB pathway in AA rats …