Background: The diagnosis of COPD is based on both clinical signs and functional tests.
Although there are different functional tests used to assess COPD, no reliable biomarkers …

Background: Detection of surfactant proteins A and D (SP-A and SP-D) in the serum of
patients with pulmonary diseases is thought to reflect an injury of the alveolar epithelial …

Plasma pro-surfactant protein B (pro-SFTPB) levels have recently been shown to predict the
development of lung cancer in current and ex-smokers, but the ability of pro-SFTPB to …

Introduction Emphysema and idiopathic pulmonary fibrosis (IPF) present either per se or
coexist in combined pulmonary fibrosis and emphysema (CPFE). Serum surfactant proteins …

Rationale & Aim Pulmonary surfactants are essential components of lung homeostasis. In
chronic obstructive pulmonary disease (COPD), surfactant expression decreases in lungs …

Surfactant proteins (SPs) have been studied in COPD patients as biomarkers of disease
severity and as predictive factors of unfavorable outcomes. The aim of this exploratory study …

Purpose Pulmonary surfactant proteins A (SP-A) and D (SP-D) are lectins, involved in host
defense and regulation of pulmonary inflammatory response. However, studies on the …

Pulmonary surfactant protein D (SP-D) is considered a candidate biomarker for lung integrity
and for disease progression. In the present study, we aimed to estimate the serum levels of …

Abstract Background Pulmonary surfactant D (SP-D) has important regulatory functions for
innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary …

Background: The exacerbation of chronic obstructive pulmonary disease (COPD) is a major
factor for the high mortality associated with the disease. There is a paucity in the lung …