Is there a dark side to long-term proton pump inhibitor therapy?

TB Nealis, CW Howden - American journal of therapeutics, 2008 - journals.lww.com
Proton pump inhibitors (PPIs) are among the most widely used of prescription drugs. They
have revolutionized the management of gastroesophageal reflux disease and other acid …

Long-term safety concerns with proton pump inhibitors

T Ali, DN Roberts, WM Tierney - The American journal of medicine, 2009 - Elsevier
Proton pump inhibitors (PPIs) are among the most widely prescribed medications worldwide.
Their use has resulted in dramatic improvements in treatment of peptic ulcer disease and …

[PDF][PDF] Proton pump inhibitors: the good, the bad, and the unwanted

S Chubineh, J Birk - South Med J, 2012 - sma.org
Proton pump inhibitors (PPIs) are one of the most commonly prescribed classes of
medications in the United States. By inhibiting gastric H+/K+ adenosine triphosphatase via …

Proton pump inhibitors: what the internist needs to know

SJ Spechler - Medical Clinics, 2019 - medical.theclinics.com
Proton pump inhibitors (PPIs) are among the most commonly used and overprescribed
medications in the world. 1 In the United States alone, more than 7% of adults take …

Considerations for long-term use of proton-pump inhibitors

WR Garnett - American journal of health-system pharmacy, 1998 - academic.oup.com
The safety of proton-pump inhibitors (PPIs) for long-term use is reviewed. PPIs are being
used with increasing frequency to inhibit secretion of gastric acid in order to treat acid …

The use and misuse of proton pump inhibitors: an opportunity for deprescribing

TS Dharmarajan - Journal of the American Medical Directors Association, 2021 - Elsevier
Proton pump inhibitors (PPIs) are proven medications of choice for gastroesophageal reflux
disease (GERD), acid-related disorders, erosive esophagitis, Barrett esophagus, prevention …

[HTML][HTML] Advantages and disadvantages of long-term proton pump inhibitor use

Y Kinoshita, N Ishimura, S Ishihara - … of neurogastroenterology and …, 2018 - ncbi.nlm.nih.gov
Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for
treatment of acid-related diseases including gastroesophageal reflux disease and …

[HTML][HTML] The role of proton pump inhibitors in the management of upper gastrointestinal disorders

MA Khan, CW Howden - Gastroenterology & hepatology, 2018 - ncbi.nlm.nih.gov
Proton pump inhibitors (PPIs) have been in use since the early 1990s and play a crucial role
in the management of a number of conditions affecting the upper gastrointestinal tract …

Adverse effects of proton pump inhibitors

F Lodato, F Azzaroli, L Turco, N Mazzella… - Best practice & research …, 2010 - Elsevier
Proton pump inhibitors (PPI) are very effective drugs used largely in acid related disorders.
During the last years concern have been raised regarding their overutilisation in benign …

[PDF][PDF] Adverse effects associated with proton pump inhibitor use

M Yibirin, D De Oliveira, R Valera, AE Plitt, S Lutgen… - Cureus, 2021 - cureus.com
Proton pump inhibitors (PPIs) marked a before and after in the management of gastric acid‐
related disorders since their introduction to the market in 1989. Due to a novel, highly …