Melatonin, a hormone produced in the pineal gland, has been investigated for bone repair,
remodeling, osteoporosis, as well as osseointegration of the implants. In this study, different …

Silks are being reassessed as biomaterial scaffolds due to their unique mechanical
properties, opportunities for genetic tailoring of structure and thus function, and recent …

Melatonin promotes bone formation and prevents bone degradation via receptor‐dependent
or receptor‐independent actions. The aim of this study is to encapsulate melatonin into poly …

In terms of a novel scaffold with well good osteoinductive and osteoconductive capacity,
melatonin (Mel) possesses positive effects on chemical linkage in scaffold structures, which …

The repair of critical-sized bone defects poses a significant challenge due to the absence of
periosteum, which plays a crucial role in coordinating the processes of osteogenesis and …

Sustained release of a bioactive agent from a tissue engineering scaffold is one of the most
common strategies to improve regenerative potential of the construct. However, depending …

The development of hybrid scaffolds mimicking the extracellular matrix with bioactive factors
has great potential to regenerate tissues in tissue engineering and wound-healing …

Silk is a natural fibrous polymer with application potential in regenerative medicine.
Increasing interest remains for silk materials in bone tissue engineering due to their …

Electrospraying assures many advantages with taking less time and costing less relatively to
the other conventional particle production methods. In this research, we investigated the …

To control the sustained release of melatonin and modulate the osteogenic differentiation of
mesenchymal stem cells (MSCs), melatonin was firstly loaded onto TiO2 nanotubes by direct …