Molecular spectra and frequency patterns of somatic mutations in Arab women with breast cancer

HO Al-Shamsi, I Abu-Gheida, AS Abdulsamad… - The …, 2021 - academic.oup.com
Background The role of somatic mutations in breast cancer prognosis and management
continues to be recognized. However, data on the molecular profiles of Arab women are …

[HTML][HTML] Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients

DH Barakeh, R Aljelaify, Y Bashawri, A Almutairi… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Breast cancer (BCa) ranks first in incidence rate among cancers in Arab females. The
association between genetic polymorphisms in tumor suppressor genes and the risk of BCa …

[HTML][HTML] Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients

A Nassar, M Abouelhoda, O Mansour, SA Loutfy… - Journal of Advanced …, 2020 - Elsevier
Breast cancer (BC) incidence is progressively increasing in Egypt. However, there is
insufficient knowledge of the acquired somatic mutations in Egyptian BC patients which limit …

[HTML][HTML] Mutation Spectrum Comparison between Benign Breast Lesion Cohort, Unselected Cancer Cohort and High-Risk Breast Cancer Cohort

A Kwong, CYS Ho, HCM Leung, AWS Leung, CH Au… - Cancers, 2024 - mdpi.com
Simple Summary Germline mutation rates and spectra across three cohorts of Chinese
patients: a high-risk breast cancer cohort, an unselected breast cancer cohort, and a benign …

Mutational signatures in breast cancer: the problem at the DNA level

S Nik-Zainal, S Morganella - Clinical Cancer Research, 2017 - AACR
A breast cancer genome is a record of the historic mutagenic activity that has occurred
throughout the development of the tumor. Indeed, every mutation may be informative …

Somatic Mutations in Latin American Breast Cancer Patients: A Systematic Review and Meta-Analysis

GA Martínez-Nava, LK Urbina-Jara, S Lira-Albarrán… - Diagnostics, 2024 - mdpi.com
(1) Background: Somatic mutations may be connected to the exposome, potentially playing
a role in breast cancer's development and clinical outcomes. There needs to be information …

Association of Pathway Mutations With Survival in Taiwanese Breast Cancers

PS Yang, YT Chao, CF Lung, CL Liu, YC Chang… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the most common invasive cancer in women worldwide. Next-generation
sequencing (NGS) provides a high-resolution profile of cancer genome. Our study ultimately …

[HTML][HTML] Pathway mutations in breast cancer using whole-exome sequencing

YS Chang, CM Chang, CY Lin, DS Chao… - Oncology …, 2020 - ncbi.nlm.nih.gov
The genomic landscape of breast cancer (BC) is complex. The purpose of this study was to
decipher the mutational profiles of Taiwanese patients with BC using next-generation …

[HTML][HTML] Landscape of clinically actionable mutations in breast cancer 'A cohort study'

M Ghosh, R Naik, SM Lingaraju, SP Susheela… - Translational …, 2021 - Elsevier
Breast cancer (BC) is a heterogeneous disease. Numerous chemotherapeutic agents are
available for early stage or advanced/metastatic breast cancer to provide maximum benefit …

A comparative analysis of breast and ovarian cancer-related gene mutations in Canadian and Saudi Arabian patients with breast cancer

Y Amemiya, S Bacopulos, M Al-Shawarby… - Anticancer …, 2015 - ar.iiarjournals.org
Previous reports have indicated that patients with breast cancer who are from the Eastern
Province of Saudi Arabia have a different gene expression profile from that known for their …