Insulin like growth factor-1 (IGF-1) plays important roles in metabolic functions, especially in
adulthood. Additionally, obese subjects are reportedly predisposed to having low absolute …

BACKGROUND: Insulin-like growth factor-1 (IGF-1) is associated with obesity and aging,
and was recently linked to metabolic syndrome (MetS) and insulin resistance. However, little …

Context: Low serum IGF-1 levels have been linked to increased risk for development of type
2 diabetes. However, the physiological role of IGF-1 in glucose metabolism is not well …

Background A previous study showed an inverse association between the insulin‐like
growth factor I (IGF‐I) and the risk of impaired glucose tolerance or diabetes mellitus …

BACKGROUND AND AIM: Weight gain is associated with a decline in insulin sensitivity and
a compensatory increase in insulin secretion. IGF-1 is a plausible candidate to explain these …

OBJECTIVE Serum insulin-like growth factor (IGF)-1 may have a role in the maintenance of
glucose homeostasis. We examined the association between serum IGF-1 and diabetes in a …

OBJECTIVES: We investigated the effect of obesity on the serum levels of total and free IGF-
1 and their relationship to the circulating levels of insulin and IGF binding proteins (IGFBPs) …

Background Insulin-like growth factor-I (IGF-I) is homologous to proinsulin and possesses
glucose reducing activity. The association between the level of IGF-I and diabetes has been …

OBJECTIVE: To compare insulin-like growth factor-I (IGF-I) concentrations in obese and
normal subjects, and evaluate the possible relationships between IGF-I concentrations and …

Context: In obesity, total IGF-I is not reduced to the degree predicted by low GH levels, and
free IGF-I levels are normal to high. Total and free IGF-I may not reflect IGF-I biological …