Residual Risk of Trimethylamine‐N‐Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy

J Xue, J Xu, M Zhao, A Jin, A Cheng… - Journal of the …, 2022 - Am Heart Assoc
Background Trimethylamine N‐oxide (TMAO) contributes to cardiovascular disease through
its prothrombotic, proatherothrombotic, and proinflammatory effects. We aimed to evaluate …

Trimethylamine N-oxide and stroke recurrence depends on ischemic stroke subtypes

J Xu, A Cheng, B Song, M Zhao, J Xue, A Wang, L Dai… - Stroke, 2022 - Am Heart Assoc
Background: Trimethylamine N-oxide (TMAO) has been recognized as a risk factor for
cardiovascular disease. However, the role of TMAO in ischemic stroke remains unclear. As …

Serum trimethylamine N-oxide concentration is positively associated with first stroke in hypertensive patients

J Nie, L Xie, B Zhao, Y Li, B Qiu, F Zhu, G Li, M He… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Trimethylamine N-oxide (TMAO)—a gut derived metabolite—
has been shown to be atherogenic. It remains unknown whether TMAO is associated with …

Plasma Trimethylamine‐N‐Oxide and Incident Ischemic Stroke: The Cardiovascular Health Study and the Multi‐Ethnic Study of Atherosclerosis

RN Lemaitre, PN Jensen, Z Wang… - Journal of the …, 2023 - Am Heart Assoc
Background The association of circulating trimethylamine‐N‐oxide (TMAO) with stroke has
received limited attention. To address this gap, we examined the associations of serial …

The relationship between trimethylamine-N-oxide and the risk of acute ischemic stroke: A dose‒response meta-analysis

Y Hong, Z Sun, N Liu, K Yang, Y Li, Q Xu, Z Guo… - Plos one, 2023 - journals.plos.org
Background Although trimethylamine-N-oxide (TMAO) shows a notable correlation with
cardiovascular disease, its association with acute ischemic stroke (AIS) remains uncertain …

Trimethylamine-N-oxide levels are similar in asymptomatic vs. symptomatic cerebrovascular atherosclerosis

M Heyse, C Schneider, P Monostori… - Frontiers in …, 2021 - frontiersin.org
Introduction: Trimethylamine-N-oxide (TMAO) is correlated with atherosclerosis and vascular
diseases such as coronary heart disease and ischemic stroke. The aim of the study was to …

Associations of plasma TMAO and its precursors with stroke risk in the general population: A nested case‐control study

D Liu, S Gu, Z Zhou, Z Ma, H Zuo - Journal of Internal Medicine, 2023 - Wiley Online Library
Abstract Background Trimethylamine N‐oxide (TMAO) is a gut‐derived atherogenic
metabolite. However, the role of TMAO and its precursors in the development of stroke …

Relationship between elevated plasma trimethylamine N-oxide levels and increased stroke injury

C Wu, F Xue, Y Lian, J Zhang, D Wu, N Xie, W Chang… - Neurology, 2020 - AAN Enterprises
Objective To investigate whether elevated plasma trimethylamine N-oxide (TMAO) levels are
associated with initial stroke severity and infarct volume. Methods This cross-sectional study …

Increasing trimethylamine N-oxide levels as a predictor of early neurological deterioration in patients with acute ischemic stroke

L Hou, Y Zhang, D Zheng, H Shi, C Zou… - Neurological …, 2020 - Taylor & Francis
Background and aims: Trimethylamine N-oxide (TMAO), a pro-atherosclerotic intestinal
microbiota metabolite, has mechanistic links to atherosclerosis development and …

TMAO as a novel predictor of major adverse vascular events and recurrence in patients with large artery atherosclerotic ischemic stroke

YY Chen, ZS Ye, NG Xia, Y Xu - Clinical and Applied …, 2022 - journals.sagepub.com
Objectives To explore the association of plasma trimethylamine N-oxide (TMAO)
concentration with large artery atherosclerotic (LAA) ischemic stroke and its role in …