Hox genes in adult tissues and their role in endothelial cell differentiation and angiogenesis

E Nova-Lampeti, V Aguilera, K Oporto… - … -Old Concepts and …, 2018 - books.google.com
HOX genes belong to a family of transcription factors characterized by a 183 bp DNA
sequence called homeobox, which code for a 61-amino-acid domain defined as the …

[HTML][HTML] Deciphering the emerging landscape of HOX genes in cardiovascular biology, atherosclerosis and beyond

Y Zhou, Q Wu, Y Guo - International Journal of …, 2023 - spandidos-publications.com
Atherosclerosis, a dominant driving force underlying multiple cardiovascular events, is an
intertwined and chronic inflammatory disease characterized by lipid deposition in the arterial …

Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression

H Park, HJ Choi, J Kim, M Kim, SS Rho… - Biochemical and …, 2011 - Elsevier
Homeobox (HOX) family genes, major transcription factors for embryonic development, have
been also implicated in vascular development and angiogenesis, particularly with regulation …

[HTML][HTML] Topographic patterns of vascular disease: HOX proteins as determining factors?

RP Visconti, A Awgulewitsch - World Journal of Biological …, 2015 - ncbi.nlm.nih.gov
Steadily increasing evidence supports the idea that genetic diversities in the vascular bed
are, in addition to hemodynamic influences, a major contributing factor in determining region …

The dual roles of homeobox genes in vascularization and wound healing

S Kachgal, KA Mace, NJ Boudreau - Cell adhesion & migration, 2012 - Taylor & Francis
Homeobox genes represent a family of highly conserved transcription factors originally
discovered to regulate organ patterning during development. More recently, several …

HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2

S Winnik, M Klinkert, H Kurz, C Zoeller… - Cardiovascular …, 2009 - academic.oup.com
Abstract Aims Homeobox (Hox) proteins are transcriptional regulators in embryonic
patterning, cell differentiation, proliferation, and migration in vertebrates and invertebrates. A …

Control of vascular cell differentiation by homeobox transcription factors

DH Gorski, K Walsh - Trends in cardiovascular medicine, 2003 - Elsevier
Homeobox genes are a family of transcription factors with a highly conserved DNA-binding
domain that regulate cell proliferation, differentiation, and migration in many cell types in …

HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells

N Chung, BK Jee, SW Chae, YW Jeon, KH Lee… - Molecular biology …, 2009 - Springer
Human bone marrow-derived mesenchymal stem cells (hMSCs) have been shown to
possess multilineage differentiation potential. HOX genes function in transcriptional …

A role for Hox A5 in regulating angiogenesis and vascular patterning

K Rhoads, G Arderiu, A Charboneau… - … research and biology, 2005 - liebertpub.com
Background: Homeobox (Hox) genes are transcriptional regulators which modulate
embryonic morphogenesis and pathological tissue remodeling in adults via regulation of …

HOXC9: a key regulator of endothelial cell quiescence and vascular morphogenesis

SJ Stoll, J Kroll - Trends in Cardiovascular Medicine, 2012 - Elsevier
The members of the HOX transcription factor family are important basic regulators of
morphogenesis and development and several HOX proteins have also been identified as …