Abstract Anxiety Disorders and Posttraumatic Stress Disorders (PTSD) associated with type-
1 diabetes mellitus (T1DM) are increasingly common comorbidities and the treatment is …

Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to defects in
insulin secretion or its action. Complications from long-term diabetes consist of numerous …

Purpose Diabetes mellitus (DM) is a metabolic disorder characterized by insulin deficiency
or insulin resistance. Pregabalin (PGB) is an antiepileptic drug with proven efficacy in the …

Objectives: Pregabalin (PGB) is used in drug-resistant epilepsy. Also, it has analgesic effects
in painful syndromes. Depression and anxiety are commonly seen in epilepsy and …

BACKGROUND AND PURPOSE Impulsivity is a core symptom in many neuropsychiatric
disorders. The main objective of this study was to evaluate the effects of topiramate and …

Background: Anticonvulsants are often prescribed as coanalgesics for pathologies
presenting chronic pain, such as chronic neuropathic pain and fibromyalgia. These …

To evaluate the antinociceptive and hypnotic effects of pregabalin, we established a
neuropathic pain-like model in mice using partial sciatic nerve ligation (PSNL), and …

Abstract Rationale Pregabalin (Lyrica™) is a structural analogue of γ-aminobutyric acid
(GABA) approved by FDA for partial epilepsy, neuropathic pain and recently generalized …

Pregabalin is a newly developed synthetic gamma-aminobutyric acid (GABA) that is
approved for the treatment of fibromyalgia and several neuropathy. It has been proven to …

Posttraumatic stress disorder (PTSD) can be a very debilitating condition. Effective
approaches to prevent and treat PTSD are important areas of basic science research …