ZmGluTR1 is involved in chlorophyll biosynthesis and is essential for maize development

W Yang, Y Yuan, P Yang, S Li, S Ma, X Liu… - Journal of Plant …, 2023 - Elsevier
Chlorophyll is the most important carrier of photosynthesis in plants and is therefore vital for
plant growth and development. Synthesis of 5-aminolevulinic acid (ALA) is initiated and …

An alanine to valine mutation of glutamyl-tRNA reductase enhances 5-aminolevulinic acid synthesis in rice

M Jiang, S Dai, YC Zheng, RQ Li, YY Tan… - Theoretical and Applied …, 2022 - Springer
Key message An alanine to valine mutation of glutamyl-tRNA reductase's 510th amino acid
improves 5-aminolevulinic acid synthesis in rice. Abstract 5-aminolevulinic acid (ALA) is the …

The GluTR-binding protein is the heme-binding factor for feedback control of glutamyl-tRNA reductase

AS Richter, C Banse, B Grimm - Elife, 2019 - elifesciences.org
Synthesis of 5-aminolevulinic acid (ALA) is the rate-limiting step in tetrapyrrole biosynthesis
in land plants. In photosynthetic eukaryotes and many bacteria, glutamyl-tRNA reductase …

GluTR2 Complements a hema1 Mutant Lacking Glutamyl-tRNA Reductase 1, but is Differently Regulated at the Post-Translational Level

J Apitz, J Schmied, MJ Lehmann… - Plant and cell …, 2014 - academic.oup.com
Arabidopsis HEMA1 and HEMA2 encode glutamyl-tRNA reductase (GluTR) 1 and 2, the two
isoforms of the initial enzyme of tetrapyrrole biosynthesis. HEMA1 is dominantly expressed …

Controlled partitioning of glutamyl-tRNA reductase in stroma-and membrane-associated fractions affects the synthesis of 5-aminolevulinic acid

J Schmied, Z Hou, B Hedtke… - Plant and Cell Physiology, 2018 - academic.oup.com
The synthesis of 5-aminolevulinic acid (ALA) determines adequate amounts of metabolites
for the tetrapyrrole biosynthetic pathway. Glutamyl-tRNA reductase (GluTR) catalyzes the …

Posttranslational control of ALA synthesis includes GluTR degradation by Clp protease and stabilization by GluTR-binding protein

J Apitz, K Nishimura, J Schmied, A Wolf… - Plant …, 2016 - academic.oup.com
Aminolevulinic acid (ALA) is the first committed substrate of tetrapyrrole biosynthesis and is
formed from glutamyl-tRNA by two enzymatic steps. Glutamyl-tRNA reductase (GluTR) as …

Fluorescence in blue light (FLU) is involved in inactivation and localization of glutamyl‐tRNA reductase during light exposure

Z Hou, Y Yang, B Hedtke, B Grimm - The Plant Journal, 2019 - Wiley Online Library
Fluorescent in blue light (FLU) is a negative regulator involved in dark repression of 5‐
aminolevulinic acid (ALA) synthesis and interacts with glutamyl‐tRNA reductase (GluTR) …

Proteomic and functional analysis of soybean chlorophyll-deficient mutant cd1 and the underlying gene encoding the CHLI subunit of Mg-chelatase

H Du, M Qi, X Cui, Y Cui, H Yang, J Zhang, Y Ma… - Molecular …, 2018 - Springer
Sufficient chlorophyll biosynthesis is vital for the growth of photoautotrophic plants. Mg-
chelatase, consisting of three subunits (CHLI, CHLD, and CHLH), catalyzes the insertion of …

Glutamate 1-semialdehyde aminotransferase is connected to GluTR by GluTR-binding protein and contributes to the rate-limiting step of 5-aminolevulinic acid …

N Sinha, J Eirich, I Finkemeier, B Grimm - The Plant Cell, 2022 - academic.oup.com
Tetrapyrroles play fundamental roles in crucial processes including photosynthesis,
respiration, and catalysis. In plants, 5-aminolevulinic acid (ALA) is the common precursor of …

Overexpression of HEMA1 encoding glutamyl-tRNA reductase

J Schmied, B Hedtke, B Grimm - Journal of plant physiology, 2011 - Elsevier
5-Aminolevulinic acid (ALA) synthesis has been shown to be the rate limiting step of
tetrapyrrole biosynthesis. Glutamyl-tRNA reductase (GluTR) is the first committed enzyme of …