Aim: Obesity is a major contributor to the global burden of disease and is closely associated
with the development of type 2 diabetes and cardiovascular diseases. This study tested the …

Background Pathophysiological processes underlying diabetic-related cardiomyopathies
are complex. Mitochondria dysfunction is often described as a cause of cardiac impairment …

Diabetes is a chronic disease associated to a cardiac contractile dysfunction that is not
attributable to underlying coronary artery disease or hypertension, and could be …

Although incidence and prevalence of prediabetes are increasing, little is known about its
cardiac effects. Therefore, our aim was to investigate the effect of prediabetes on cardiac …

Aim: The incidence of coronary heart diseases (CHD), congestive heart failure (CHF) and
myocardial infarction is higher in diabetic patients than in non‐diabetic groups, with these …

The objective of this study was to determine whether a defect in mitochondrial respiratory
function accompanies the development of diabetic cardiomyopathy. The hypothesis tested in …

Background—Obesity is a risk factor for cardiovascular disease and is strongly associated
with insulin resistance and type 2 diabetes. Recent studies in obese humans and animals …

Rationale Our recent study suggested that ischemia–reperfusion (I/R) induced oxidative
stress was minimal in the rat heart during initial stage of diabetes and the one that …

Background—Obesity and diabetes mellitus are independently associated with the
development of heart failure. In this study, we determined the respective effects of obesity …

This study examined the impact of physical training on cardiac mitochondrial respiration of
rats with chronic diabetes mellitus. Diabetes was induced by an intravenous injection of STZ …