A genome-wide profiling of the humoral immune response to Chlamydia trachomatis infection reveals vaccine candidate antigens expressed in humans
J Wang, Y Zhang, C Lu, L Lei, P Yu… - The Journal of …, 2010 - journals.aai.org
A whole genome scale proteome array consisting of 908 open reading frames encoded in
Chlamydia trachomatis genome and plasmid was used to profile anti-chlamydial Ab …
Chlamydia trachomatis genome and plasmid was used to profile anti-chlamydial Ab …
P479 Immunoprofiling of Chlamydia trachomatis combining whole-proteome microarrays and high-throughput multiplex serology
K Hufnagel, N Gassert, J Butt… - Sexually Transmitted …, 2019 - search.proquest.com
Background Chronic infections with Chlamydia trachomatis (Ct) can give rise to sequelae
that include pelvic inflammatory disease (PID), chronic pelvic pain (CPP), ectopic pregnancy …
that include pelvic inflammatory disease (PID), chronic pelvic pain (CPP), ectopic pregnancy …
[HTML][HTML] Chlamydia trachomatis Whole-Proteome Microarray Analysis of The Netherlands Chlamydia Cohort Study
K Hufnagel, B Hoenderboom, C Harmel, JK Rohland… - Microorganisms, 2019 - mdpi.com
Chlamydia trachomatis (Ct) whole-proteome microarrays were utilized to identify antibody
patterns associated with infection; pelvic inflammatory disease (PID), tubal factor infertility …
patterns associated with infection; pelvic inflammatory disease (PID), tubal factor infertility …
Proteome array of antibody responses to Chlamydia trachomatis infection in nonhuman primates
C Lu, Z Sun, H Chen, L Chen, C Zhu, C Chen, C Li… - Life sciences, 2020 - Elsevier
Aims Nonhuman primates have been used to investigate pathogenic mechanisms and
evaluate immune responses following Chlamydia trachomatis inoculation. This study aimed …
evaluate immune responses following Chlamydia trachomatis inoculation. This study aimed …
Identification of immunodominant antigens of Chlamydia trachomatis using proteome microarrays
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen in the
world. In order to control this infection there is an urgent need to formulate a vaccine …
world. In order to control this infection there is an urgent need to formulate a vaccine …
High-throughput proteomic screening identifies Chlamydia trachomatis antigens that are capable of eliciting T cell and antibody responses that provide protection …
MD Picard, KP Cohane, TM Gierahn, DE Higgins… - Vaccine, 2012 - Elsevier
A comprehensive proteomic screening technology was previously used to characterize T
cell responses to Chlamydia trachomatis infection. In this study, we demonstrated that T cells …
cell responses to Chlamydia trachomatis infection. In this study, we demonstrated that T cells …
Whole genome identification of C. trachomatis immunodominant antigens after genital tract infections and effect of antibiotic treatment of pigtailed macaques
DL Patton, A Teng, A Randall, X Liang, PL Felgner… - Journal of …, 2014 - Elsevier
The cervix and/or fallopian tubes of pigtailed macaques were experimentally infected with
Chlamydia trachomatis. Their sera were collected at varying time points and screened for …
Chlamydia trachomatis. Their sera were collected at varying time points and screened for …
Identification of Immunodominant Antigens by Probing a Whole Chlamydia trachomatis Open Reading Frame Proteome Microarray Using Sera from Immunized Mice
MI Cruz-Fisher, C Cheng, G Sun, S Pal… - Infection and …, 2011 - Am Soc Microbiol
Chlamydia trachomatis infections can lead to severe chronic complications, including
trachoma, ectopic pregnancy, and infertility. The only effective approach to disease control is …
trachoma, ectopic pregnancy, and infertility. The only effective approach to disease control is …
Profiling of Human Antibody Responses to Chlamydia trachomatis Urogenital Tract Infection Using Microplates Arrayed with 156 Chlamydial Fusion Proteins
J Sharma, Y Zhong, F Dong, JM Piper… - Infection and …, 2006 - Am Soc Microbiol
The available chlamydial genome sequences have made it possible to comprehensively
analyze host responses to all chlamydial proteins, which is essential for further …
analyze host responses to all chlamydial proteins, which is essential for further …
[HTML][HTML] Immunoprofiling of Chlamydia trachomatis using whole-proteome microarrays generated by on-chip in situ expression
K Hufnagel, S Lueong, M Willhauck-Fleckenstein… - Scientific reports, 2018 - nature.com
Abstract Using Chlamydia trachomatis (Ct) as a complex model organism, we describe a
method to generate bacterial whole-proteome microarrays using cell-free, on-chip protein …
method to generate bacterial whole-proteome microarrays using cell-free, on-chip protein …