Mechanobiology aims to establish functional relationships between the mechanical state of
a living a cell and its physiology. The acquisition of force–distance curves with an AFM is by …

AFM-based force–distance curves are commonly used to characterize the nanomechanical
properties of live cells. The transformation of these curves into nanomechanical properties …

Understanding the relationship between the mechanical properties of living cells and
physiology is a central issue in mechanobiology. Mechanical properties are used as …

Currently, biomechanics of living cells is in the focus of interest due to noticeable capability
of such techniques like atomic force microscopy (AFM) to probe cellular properties at the …

Cells are constantly exposed to mechanical stimuli in their environment and have several
evolved mechanisms to sense and respond to these cues. It is becoming increasingly …

Recent findings clearly demonstrate that cells feel mechanical forces, and respond by
altering their phenotype and modulating their mechanical environment. Atomic force …

Atomic force microscopy (AFM) has become the most commonly used tool to measure the
mechanical properties of biological cells. In AFM indentation experiments, the Hertz and …

Here we overview and further develop a quantitative method to measure mechanics of
biological cells in indentation experiments, which is based on the use of atomic force …

The measurement of viscoelasticity of cells in physiological environments with high spatio-
temporal resolution is a key goal in cell mechanobiology. Traditionally only the elastic …

The elastic response of a living cell is affected by its physiological state. This property
provides mechanical fingerprints of a cell's dysfunctionality. The softness (kilopascal range) …