Neuroscience-driven discovery and development of sleep therapeutics
M Dresler, VI Spoormaker, P Beitinger, M Czisch… - Pharmacology & …, 2014 - Elsevier
Until recently, neuroscience has given sleep research and discovery of better treatments of
sleep disturbances little attention, despite the fact that disturbed sleep has overwhelming …
sleep disturbances little attention, despite the fact that disturbed sleep has overwhelming …
Sleep and sleep disturbances: biological basis and clinical implications
N Zisapel - Cellular and Molecular Life Sciences, 2007 - Springer
Sleep is a neurochemical process involving sleep promoting and arousal centers in the
brain. Sleep performs an essential restorative function and facilitates memory consolidation …
brain. Sleep performs an essential restorative function and facilitates memory consolidation …
A new dawn in the sleep disorders pipeline?
W Ockert - Nature reviews. Drug discovery, 2012 - nature.com
Sleep is a crucially important and evolutionarily conserved process across the animal
kingdom. Mammalian sleep states are characterized by altered brain activity in the rapid eye …
kingdom. Mammalian sleep states are characterized by altered brain activity in the rapid eye …
[HTML][HTML] Sleep medicine: Practice, challenges and new frontiers
Sleep medicine is an ambitious cross-disciplinary challenge, requiring the mutual
integration between complementary specialists in order to build a solid framework. Although …
integration between complementary specialists in order to build a solid framework. Although …
Basic sleep mechanisms: an integrative review
E Murillo-Rodriguez, O Arias-Carrion… - … System Agents in …, 2012 - ingentaconnect.com
Regulation of the sleep-waking cycle is complex and involves diverse brain circuits and
molecules. On one hand, an interplay among many neuroanatomical and neurochemical …
molecules. On one hand, an interplay among many neuroanatomical and neurochemical …
[HTML][HTML] Perspective on sleep and aging
AA Monjan - Frontiers in neurology, 2010 - frontiersin.org
There is a strong body of data directly interrelating sleep problems with mood disorders.
There is a growing data base directly associating sleep disorders with attention and memory …
There is a growing data base directly associating sleep disorders with attention and memory …
Genomic and proteomic approaches towards an understanding of sleep
BF O'Hara, J Ding, RL Bernat… - CNS & Neurological …, 2007 - ingentaconnect.com
The basic functions of sleep are still unclear, however, recent advances in genomics and
proteomics have begun to contribute to our understanding of both normal and pathological …
proteomics have begun to contribute to our understanding of both normal and pathological …
Sleep and its disorders in translational medicine
LM Paterson, DJ Nutt, SJ Wilson - Journal of …, 2011 - journals.sagepub.com
The study of sleep is a useful approach to studying the brain in psychiatric disorders and in
investigating the effects of psychotropic drugs. Sleep physiology lends itself well to …
investigating the effects of psychotropic drugs. Sleep physiology lends itself well to …
[图书][B] Neurochemistry of sleep and wakefulness
J Monti, SR Pandi-Perumal, CM Sinton - 2008 - books.google.com
Pharmacological approaches to our understanding of sleep have been at the forefront of
sleep research for many years. Traditional techniques have included the use of …
sleep research for many years. Traditional techniques have included the use of …
Emerging therapeutics in sleep
CB Saper, TE Scammell - Annals of neurology, 2013 - Wiley Online Library
The development of new therapeutics for sleep disorders is increasingly dependent upon
understanding the basic brain circuitry that underlies sleep–wake regulation, and how it may …
understanding the basic brain circuitry that underlies sleep–wake regulation, and how it may …