Vigorous virus-specific CD4+ T-helper-cell responses are associated with successful control
of hepatitis C virus (HCV) and other human viral infections, but the breadth and specificity of …

A vigorous hepatitis C virus (HCV)-specific Th cell response is regarded as essential to the
immunological control of HCV viremia. The aim of this study was to comprehensively define …

Hepatitis C virus (HCV)‐specific CD4+ and CD8+ T cell responses were investigated using
a panel of 728 overlapping peptides spanning the whole HCV genome in 47 HCV mono …

The hepatitis C virus (HCV)-specific CD8+-T-cell response is thought to play a critical role in
HCV infection. Studies of these responses have largely relied on the analysis of a small …

This study was performed to compare the vigor and phenotype of virus-specific CD4+ and
CD8+ T-cell responses in patients with different virologic and clinical outcomes after …

Hepatitis C virus (HCV)-specific T-cell responses are rarely detected in peripheral blood,
especially in the presence of human immunodeficiency virus (HIV) coinfection. Based on …

Abstract Virus-specific CD4+ T-cell response at the site of inflammation is believed to play a
decisive role for the course of viral disease. In hepatitis C virus (HCV) infection, the majority …

Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is
likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses …

Hepatitis C virus (HCV)-specific T cell responses are closely linked to the clinical course of
infection. While T cell responses in self-limiting infection are typically broad and multi …

The cellular immune response contributes to clearance of hepatitis C virus (HCV) and
persists for decades after recovery from infection. The immunological basis for the …