Re-print of “Radical Delivery and Fragmentation for Structural Analysis of Glycerophospholipids”

HT Pham, RR Julian - International Journal of Mass Spectrometry, 2015 - Elsevier
Conventional tandem mass spectrometry relies on even-electron fragmentation that
provides limited structural information for glycerophospholipids (GP), which are key …

Radical delivery and fragmentation for structural analysis of glycerophospholipids

HT Pham, RR Julian - International Journal of Mass Spectrometry, 2014 - Elsevier
Conventional tandem mass spectrometry relies on even-electron fragmentation that
provides limited structural information for glycerophospholipids (GP), which are key …

Pinpointing Double Bond and sn-Positions in Glycerophospholipids via Hybrid 193 nm Ultraviolet Photodissociation (UVPD) Mass Spectrometry

PE Williams, DR Klein, SM Greer… - Journal of the American …, 2017 - ACS Publications
Complete structural characterization of complex lipids, such as glycerophospholipids, by
tandem mass spectrometry (MS/MS) continues to present a major challenge. Conventional …

Coupling headgroup and alkene specific solution modifications with gas-phase ion/ion reactions for sensitive glycerophospholipid identification and characterization

ET Franklin, SWJ Shields, JM Manthorpe… - Journal of the …, 2020 - ACS Publications
Shotgun lipidomics provides sensitive and fast lipid identification without the need for
chromatographic separation. Challenges faced by shotgun analysis of glycerophospholipids …

Localization of cyclopropyl groups and alkenes within glycerophospholipids using gas‐phase ion/ion chemistry

DSM Shenault, SA McLuckey… - Journal of Mass …, 2023 - Wiley Online Library
Shotgun lipid analysis using electrospray ionization tandem mass spectrometry (ESI‐
MS/MS) is a common approach for the identification and characterization of …

Electron‐induced dissociation (EID) for structure characterization of glycerophosphatidylcholine: determination of double‐bond positions and localization of acyl …

JW Jones, CJ Thompson, CL Carter… - Journal of Mass …, 2015 - Wiley Online Library
Glycerophospholipids are a highly abundant and diverse collection of biologically relevant
lipids, and distinction between isomeric and isobaric species is a fundamental aspect for …

[HTML][HTML] A rapid ambient ionization-mass spectrometry approach to monitoring the relative abundance of isomeric glycerophospholipids

RL Kozlowski, TW Mitchell, SJ Blanksby - Scientific reports, 2015 - nature.com
Glycerophospholipids with two, non-equivalent fatty acyl chains can adopt one of two
isomeric forms depending on the relative position of substitutions on the glycerol backbone …

Structural elucidation of ether glycerophospholipids using gas-phase ion/ion charge inversion chemistry

CE Randolph, DSM Shenault… - Journal of the …, 2020 - ACS Publications
Ether lipids represent a unique subclass of glycerophospholipid (GPL) that possesses a 1-O-
alkyl (ie, plasmanyl subclass) or a 1-O-alk-1′-enyl (ie, plasmenyl subclass) group linked at …

Electrospray ionization with low-energy collisionally activated dissociation tandem mass spectrometry of glycerophospholipids: mechanisms of fragmentation and …

FF Hsu, J Turk - Journal of Chromatography B, 2009 - Elsevier
This review describes the use of low-energy collisionally activated dissociation (CAD) with
both tandem quadrupole and ion-trap mass spectrometry toward structural characterization …

Functional group selective derivatization and gas-phase fragmentation reactions of plasmalogen glycerophospholipids

CJ Fhaner, S Liu, X Zhou, GE Reid - Mass spectrometry, 2013 - jstage.jst.go.jp
A reaction strategy involving functional group selective modification of the O-alkenyl-ether
double bond within plasmenyl ether containing lipids using iodine and methanol, in …