[HTML][HTML] The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets
Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and
genetically heterogeneous malignancies, characterized by distinct prognoses based upon …
genetically heterogeneous malignancies, characterized by distinct prognoses based upon …
Overview of the 2022 WHO classification of neuroendocrine neoplasms
In this review, we detail the changes and the relevant features that are applied to
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …
[HTML][HTML] Genetic and epigenetic drivers of neuroendocrine tumours (NET)
A Di Domenico, T Wiedmer, I Marinoni… - Endocrine-related …, 2017 - erc.bioscientifica.com
Neuroendocrine tumours (NET) of the gastrointestinal tract and the lung are a rare and
heterogeneous group of tumours. The molecular characterization and the clinical …
heterogeneous group of tumours. The molecular characterization and the clinical …
[HTML][HTML] Genomic landscape of pancreatic neuroendocrine tumours: the International Cancer Genome Consortium
A Mafficini, A Scarpa - Journal of Endocrinology, 2018 - joe.bioscientifica.com
Neuroendocrine tumours (NETs) may arise throughout the body and are a highly
heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of …
heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of …
[HTML][HTML] The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms
A Venizelos, H Elvebakken, A Perren… - Endocrine-related …, 2022 - erc.bioscientifica.com
High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare
but have a very poor prognosis and represent a severely understudied class of tumours …
but have a very poor prognosis and represent a severely understudied class of tumours …
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors
P Cejas, Y Drier, KMA Dreijerink, LAA Brosens… - Nature medicine, 2019 - nature.com
Most pancreatic neuroendocrine tumors (PNETs) do not produce excess hormones and are
therefore considered 'non-functional',–. As clinical behaviors vary widely and distant …
therefore considered 'non-functional',–. As clinical behaviors vary widely and distant …
Genetics and epigenetics of gastroenteropancreatic neuroendocrine neoplasms
A Mafficini, A Scarpa - Endocrine reviews, 2019 - academic.oup.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …
[HTML][HTML] An organoid biobank of neuroendocrine neoplasms enables genotype-phenotype mapping
K Kawasaki, K Toshimitsu, M Matano, M Fujita, M Fujii… - Cell, 2020 - cell.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasm (NEN) that consists of
neuroendocrine tumor and neuroendocrine carcinoma (NEC) is a lethal but under …
neuroendocrine tumor and neuroendocrine carcinoma (NEC) is a lethal but under …
[HTML][HTML] Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …
whose causation is only partly understood. An increasing number of studies have uncovered …
Biology and evolution of poorly differentiated neuroendocrine tumors
Neuroendocrine (NE) cancers are a diverse group of neoplasms typically diagnosed and
treated on the basis of their site of origin. This Perspective focuses on advances in our …
treated on the basis of their site of origin. This Perspective focuses on advances in our …
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