Problem The diagnosis of microbial invasion of the amniotic cavity (MIAC) has been
traditionally performed using traditional cultivation techniques, which require growth of …

Citation DiGiulio DB, Romero R, Kusanovic JP, Gómez R, Kim CJ, Seok K, Gotsch F, Mazaki‐
Tovi S, Vaisbuch E, Sanders K, Bik EM, Chaiworapongsa T, Oyarzún E, Relman DA …

PROBLEM: Subclinical microbial invasion of the amniotic cavity occurs in 18.8% of women
with term labor and intact membranes and in 34% of patients with term PROM and is a risk …

Objective: Preterm birth is associated with 5–18% of pregnancies and is the leading cause
of neonatal morbidity and mortality. Amniotic fluid (AF) interleukin-6 (IL-6) is a key cytokine …

Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …

Background Microbial invasion of the amniotic cavity resulting in intra-amniotic infection is
associated with obstetrical complications such as preterm labor with intact or ruptured …

Objective Microbial invasion of the amniotic cavity (MIAC) is common in early preterm labor
and is associated with maternal and neonatal infectious morbidity. MIAC is usually occult …

Introduction: The objectives of this study were: 1) to determine the amniotic fluid (AF)
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …

Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …

Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …