Background Specific medical conditions are more prevalent in Down syndrome (DS)
compared to the general population. Medical heterogeneity has also been hypothesized to …

Individuals with Down syndrome (DS) experience a range of medical and
neurodevelopmental conditions, necessitating systematic study of their occurrence and …

Background Down syndrome (DS) is associated with variable intellectual disability and
multiple health and psychiatric comorbidities. The impact of such comorbidities on cognitive …

The Down syndrome (DS) phenotype is usually characterized by relative strengths in non-
verbal skills and deficits in verbal processing, but high interindividual variability has been …

The cause of the high degree of variability in cognition and behavior among individuals with
Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in …

BACKGROUND: Many health conditions have been described in children with Down
syndrome (DS). However, there are little comparative population-based data available …

Introduction: Children and young adults with Down syndrome can demonstrate increased
behavior problems compared to their typically developing peers through childhood and …

Background Down syndrome (DS) has a unique medical and psychological profile that
could impact how health is defined on three dimensions: physical, social and mental well …

Background Down syndrome (DS) generally predisposes children to a pattern of relative
developmental strengths and challenges, but within‐syndrome heterogeneity is also …

Background There is a high degree of inter-and intra-individual variability observed within
the phenotype of Down syndrome. The Down Syndrome Cognition Project was formed to …