Role of impaired mitochondrial dynamics processes in the pathogenesis of Alzheimer's disease
AV Blagov, AV Grechko, NG Nikiforov… - International Journal of …, 2022 - mdpi.com
Mitochondrial dysfunction is now recognized as a contributing factor to neurodegenerative
diseases, including Alzheimer's disease (AD). Mitochondria are signaling organelles with a …
diseases, including Alzheimer's disease (AD). Mitochondria are signaling organelles with a …
[HTML][HTML] Mitochondrial dynamics and transport in Alzheimer's disease
PJ Flannery, E Trushina - Molecular and Cellular Neuroscience, 2019 - Elsevier
Mitochondrial dysfunction is now recognized as a contributing factor to the early pathology of
multiple human conditions including neurodegenerative diseases. Mitochondria are …
multiple human conditions including neurodegenerative diseases. Mitochondria are …
Abnormal mitochondrial dynamics—a novel therapeutic target for Alzheimer's disease?
Mitochondria are dynamic organelles that undergo continuous fission and fusion, which
could affect all aspects of mitochondrial function. Mitochondrial dysfunction has been well …
could affect all aspects of mitochondrial function. Mitochondrial dysfunction has been well …
Alterations in mitochondrial quality control in Alzheimer's disease
Q Cai, P Tammineni - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Mitochondrial dysfunction is one of the earliest and most prominent features in the brains of
Alzheimer's disease (AD) patients. Recent studies suggest that mitochondrial dysfunction …
Alzheimer's disease (AD) patients. Recent studies suggest that mitochondrial dysfunction …
Mitochondrial dynamics: a key role in neurodegeneration and a potential target for neurodegenerative disease
D Yang, J Ying, X Wang, T Zhao, S Yoon… - Frontiers in …, 2021 - frontiersin.org
In neurodegenerative diseases, neurodegeneration has been related to several
mitochondrial dynamics imbalances such as excessive fragmentation of mitochondria …
mitochondrial dynamics imbalances such as excessive fragmentation of mitochondria …
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
Mitochondrial dysfunction is one of the most early and prominent features in vulnerable
neurons in the brain of Alzheimer's disease (AD) patients. Recent studies suggest that …
neurons in the brain of Alzheimer's disease (AD) patients. Recent studies suggest that …
Mechanisms of mitochondrial malfunction in Alzheimer's disease: new therapeutic hope
Mitochondria play a critical role in neuron viability or death as it regulates energy
metabolism and cell death pathways. They are essential for cellular energy metabolism …
metabolism and cell death pathways. They are essential for cellular energy metabolism …
Mitochondrial dysfunction as a driver of cognitive impairment in Alzheimer's disease
Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and
cognitive impairment, and there are currently no broadly effective therapies. The underlying …
cognitive impairment, and there are currently no broadly effective therapies. The underlying …
Disturbed mitochondrial dynamics and neurodegenerative disorders
Mitochondria form a highly interconnected tubular network throughout the cell via a dynamic
process, with mitochondrial segments fusing and breaking apart continuously. Strong …
process, with mitochondrial segments fusing and breaking apart continuously. Strong …
Mitochondrial perturbation in Alzheimer's disease and diabetes
F Akhter, D Chen, SF Yan, SS Yan - Progress in molecular biology and …, 2017 - Elsevier
Mitochondria are well-known cellular organelles that play a vital role in cellular
bioenergetics, heme biosynthesis, thermogenesis, calcium homeostasis, lipid catabolism …
bioenergetics, heme biosynthesis, thermogenesis, calcium homeostasis, lipid catabolism …