Background Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce
alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD) …

Growing evidence indicates that the glucagon-like peptide-1 (GLP-1) system is involved in
the neurobiology of addictive behaviors, and GLP-1 analogues may be used for the …

Although the multifaceted mechanisms underlying alcohol use disorder (AUD) have been
partially defined, the neurobiological complexity of this disorder is yet to be unraveled. One …

Alcohol use disorder (AUD) is a chronic relapsing condition characterized by compulsive
alcohol-seeking behaviors, with serious detrimental health consequences. Despite high …

Background Alcohol use disorder (AUD) is a chronic, relapsing brain disorder that accounts
for 5% of deaths annually, and there is an urgent need to develop new targets for …

Abstract Glucagon-like peptide 1 (GLP-1), an incretin hormone that reduces food intake, was
recently established as a novel regulator of alcohol-mediated behaviors. Clinically available …

Background Preclinical studies in rodents have demonstrated inhibitory effects of glucagon-
like peptide-1 (GLP-1) receptor stimulation on alcohol consumption. The effects of GLP-1 …

GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use
disorders | Nature Medicine Skip to main content Thank you for visiting nature.com. You are …

The hormone glucagon-like peptide-1 (GLP-1) regulates appetite and food intake. GLP-1
receptor (GLP-1R) activation also attenuates the reinforcing properties of alcohol in rodents …

Development of alcohol use disorders largely depends on the effects of alcohol on the brain
reward systems. Emerging evidence indicate that common mechanisms regulate food and …