[HTML][HTML] Immunological role and prognostic value of somatostatin receptor family members in colon adenocarcinoma

X Yu, X Yang, H Nie, W Jiang, X He… - Frontiers in Pharmacology, 2023 - frontiersin.org
Colon adenocarcinoma (COAD) is among the most prevalent cancers worldwide, ranking as
the third most prevalent malignancy in incidence and mortality. The somatostatin receptor …

Immunohistochemical expression of somatostatin receptor subtypes 2 and 5 in colorectal cancer

I Evangelou, C Petraki, P Msaouel… - European journal of …, 2012 - Wiley Online Library
Eur J Clin Invest 2012; 42 (7): 777–783 Abstract Background To determine the
immunohistochemical expression levels of the somatostatin receptor subtypes 2 and 5 (Sst2 …

Prognostic value of somatostatin receptor subtype 2 expression in colorectal cancer

CC Raggi, F Cianchi, R Valanzano, MC Smith… - Regulatory peptides, 2005 - Elsevier
The clinical relevance of the somatostatin receptor subtype 2 (sst2) is well defined in
neuroendocrine tumors but it is still a matter of debate whether its expression may have a …

[HTML][HTML] Relationship between somatostatin receptor subtype expression and clinicopathology, Ki-67, Bcl-2 and p53 in colorectal cancer

CZ Qiu, C Wang, ZX Huang, SZ Zhu… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To study the SSTR1, 2, 3, 4, 5 expression and their relationships with clinico-
pathological factors, cell proliferation, Bcl-2 and p53 expression in colorectal cancer cells …

[HTML][HTML] Somatostatin and its receptor system in colorectal cancer

A Kasprzak - Biomedicines, 2021 - mdpi.com
Somatostatin (SST)/somatotropin release-inhibiting factor (SRIF) is a well-known
neuropeptide, widely distributed in the central and peripheral nervous systems, that …

[HTML][HTML] Expression and selective activation of somatostatin receptor subtypes induces cell cycle arrest in cancer cells

YI Zou, H Tan, Y Zhao, Y Zhou… - Oncology …, 2019 - spandidos-publications.com
Somatostatin receptors (SSTRs) are G‑protein‑coupled plasma membrane receptors that
have been determined to be expressed in normal and cancer tissues. Activation of SSTRs …

Somatostatin analogues inhibit cancer cell proliferation in an SSTR2-dependent manner via both cytostatic and cytotoxic pathways

Y Zou, X Xiao, Y Li, T Zhou - Oncology reports, 2009 - spandidos-publications.com
Somatostatin receptors (SSTRs) are inhibitory G-protein coupled receptors that are
ubiquitously expressed in normal and cancer cells. Somatostatins (SST) are the natural …

[HTML][HTML] Somatostatin receptor 2 expression profiles and their correlation with the efficacy of somatostatin analogues in gastrointestinal neuroendocrine tumors

H Watanabe, F Fujishima, I Komoto, M Imamura… - Cancers, 2022 - mdpi.com
Simple Summary Immunolocalization of somatostatin receptor 2 (SSTR2) could predict the
therapeutic efficacy of somatostatin analogues (SSAs) in neuroendocrine tumors (NETs) …

Overexpression of SSTR2 inhibited the growth of SSTR2-positive tumors via multiple signaling pathways

T Zhou, X Xiao, B Xu, H Li, Y Zou - Acta oncologica, 2009 - Taylor & Francis
Background. Somatostatin receptors (SSTR1-5) are inhibitory G-protein coupled receptors
that are ubiquitously expressed in both normal and cancer cells. Activation of SSTRs results …

[HTML][HTML] The antiproliferative effects of somatostatin receptor subtype 2 in breast cancer cells

Y He, X Yuan, P Lei, S Wu, W Xing, X Lan… - Acta Pharmacologica …, 2009 - nature.com
Aim: Somatostatin receptor subtype 2 (SSTR2) is the principal mediator of somatostatin's
(SST) antiproliferative effects on normal and cancer cells. Therefore, we investigated …