The effects of maternal aging on the localization of DNA methyltransferases were evaluated
during mouse oocyte maturation using fluorescence staining. And we conclude that …

In vertebrates, DNA methylation plays an important role in the regulation of gene expression
and embryogenesis. DNA methyltransferase, which catalyzes the introduction of a methyl …

Epigenetic mechanisms play important roles in properly occurring mammalian oogenesis.
One of these mechanisms is DNA methylation adding a methyl group to the fifth carbon atom …

DNA methylation is a key epigenetic modification which is essential for normal embryonic
development. Major epigenetic reprogramming takes place during gametogenesis and in …

Background Normal mammalian development requires the action of DNA
methyltransferases (DNMTs) for the establishment and maintenance of DNA methylation …

Purpose This study was designed to evaluate DNA methylation and the expression of DNA
methyltransferases (Dnmt1, Dnmt3a, Dnmt3b and Dnmt3L) in metaphaseII (MII) oocytes and …

In our study, we determined the progression of global DNAm during oocyte growth in
naturally cycling and hormonally stimulated mice at different time points from diestrus by …

A cultural trend in developed countries is favoring a delay in maternal age at first childbirth.
In mammals fertility and chronological age show an inverse correlation. Oocyte quality is a …

Immunofluorescence staining with antibodies against acetylated histone H4 and 5‐
methylcytosine was carried out to investigate female chromatin remodeling throughout …

The acquisition of genomic methylation in the male germ line is initiated prenatally in diploid
gonocytes, while DNA methylation in the female germ line is initiated postnatally in growing …