[PDF][PDF] Laura A. Magee, MD, Kypros H. Nicolaides, MD, and Peter von Dadelszen, D. Phil.

DL Longo - N Engl J Med, 2022 - researchgate.net
Reduced uteroplacental blood supply, increased fetoplacental demands, or both result in
uteroplacental mismatch. This leads to release of placental syncytiotrophoblast stress …

Placenta messages to the mother: not just debris

R Dechend, AC Staff - Hypertension, 2012 - Am Heart Assoc
Preeclampsia is a major pregnancy complication, affecting 5% of all pregnancies, that is
responsible for 50 000 maternal deaths annually. The only cure for preeclampsia is delivery …

Preeclampsia in 2018: revisiting concepts, physiopathology, and prediction

J Mayrink, ML Costa, JG Cecatti - The Scientific World Journal, 2018 - Wiley Online Library
Preeclampsia currently remains one of the leading causes of death and severe maternal
morbidity. Although its prevalence is still underestimated in some places due to …

[PDF][PDF] Educating Preeclampsia Management Using Case Studies of Disease Progression

A Schmidlin - 2017 - core.ac.uk
Boyd, 2016). Two blood pressure assessments exceeding 140 mm Hg systolic and/or over
90 mm Hg diastolic four hours apart in addition to proteinuria greater than 300 mg in 24 …

[HTML][HTML] Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

SE Maynard, JY Min, J Merchan… - The Journal of …, 2003 - Am Soc Clin Investig
Preeclampsia, a syndrome affecting 5% of pregnancies, causes substantial maternal and
fetal morbidity and mortality. The pathophysiology of preeclampsia remains largely …

Placental stress and pre-eclampsia: a revised view

CWG Redman, IL Sargent - Placenta, 2009 - Elsevier
In pre-eclampsia, poor placentation causes both oxidative and endoplasmic reticulum stress
of the placenta. It is believed that, in pre-eclampsia, placental hypoxia stimulates excessive …

Yijing Chu1†, Weiping Chen1†, Wei Peng1, Yong Liu2, Lin Xu1, Jianxin Zuo1, Jun Zhou1, Yan Zhang1, Ning Zhang1, Jing Li1, Ling Liu1, Ke Yao1, Guoqiang Gao1 …

Y Ye - MSC Communication in Physiological and Pathological …, 2022 - books.google.com
Preeclampsia (PE) is a hypertensive disorder during pregnancy, and is associated with
substantial maternal and perinatal complications (Hladunewich et al., 2007; Rana et al …

Human Placenta and Evolving Insights into Pathological Changes of Preeclampsia: A Comprehensive Review of the Last Decade

DM Chiorean, E Cobankent Aytekin… - Fetal and Pediatric …, 2024 - Taylor & Francis
The placenta, the foremost and multifaceted organ in fetal and maternal biology, is pivotal in
facilitating optimal intrauterine fetal development. Remarkably, despite its paramount …

Preeclampsia: pathophysiology, challenges, and perspectives

S Rana, E Lemoine, JP Granger… - Circulation …, 2019 - Am Heart Assoc
Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

OPEN ACCESS EDITED BY

B Bakrania, J Bradshaw, T Sáez… - Adverse outcomes of …, 2024 - books.google.com
Preeclampsia (PE) is a multisystem obstetric disorder that presents as new onset of
hypertension in conjunction with evidence of end-organ dysfunction beyond the 20th week …