Empowering γδ T‐cell functionality with vitamin C
D Kabelitz, L Cierna, C Juraske… - European Journal of …, 2024 - Wiley Online Library
Vitamin C (ascorbic acid) is a potent antioxidant and a cofactor for various enzymes
including histone demethylases and methylcytosine dioxygenases. Vitamin C also exerts …
including histone demethylases and methylcytosine dioxygenases. Vitamin C also exerts …
A comparative view on vitamin C effects on αβ-versus γδ T-cell activation and differentiation
C Peters, L Kouakanou… - Journal of leukocyte …, 2020 - academic.oup.com
Vitamin C (VitC) is an essential vitamin that needs to be provided through exogenous
sources. It is a potent anti-oxidant, and an essential cofactor for many enzymes including a …
sources. It is a potent anti-oxidant, and an essential cofactor for many enzymes including a …
[HTML][HTML] Vitamin C and Vitamin D—friends or foes in modulating γδ T-cell differentiation?
C Peters, K Klein, D Kabelitz - Cellular & molecular immunology, 2022 - nature.com
The differentiation and functional plasticity of T cells are transcriptionally and epigenetically
regulated by signals imposed by the local cytokine milieu and a variety of additional factors …
regulated by signals imposed by the local cytokine milieu and a variety of additional factors …
[HTML][HTML] Vitamin C promotes the proliferation and effector functions of human γδ T cells
L Kouakanou, Y Xu, C Peters, J He, Y Wu… - Cellular & Molecular …, 2020 - nature.com
Abstract γδ T cells are of interest as effector cells for cellular immunotherapy due to their
HLA-non-restricted lysis of many different tumor cell types. Potential applications include the …
HLA-non-restricted lysis of many different tumor cell types. Potential applications include the …
[HTML][HTML] Vitamin C as a promoter of γδ T cells
S Meraviglia, F Dieli - Cellular & Molecular Immunology, 2021 - nature.com
Human γδ T cells are a small CD3+ subset exhibiting features of both innate and adaptive
immune cell. 1 The major γδ T cell population in peripheral blood expresses the Vγ9 and …
immune cell. 1 The major γδ T cell population in peripheral blood expresses the Vγ9 and …
Diverse immunological roles of γδ T cells
ZW Chen - Cellular & molecular immunology, 2013 - nature.com
Accumulating evidence suggests that cd T cells play roles in host immune responses to
inflammations/damages, tumors and infections. Recent studies have demonstrated that roles …
inflammations/damages, tumors and infections. Recent studies have demonstrated that roles …
Current progress in γδ T-cell biology
T lymphocytes bearing γ-and δ-chain T-cell receptor heterodimers are named γδ T cells.
Interestingly, γδ and αβ T cells share the same progenitors, and they undergo a fate decision …
Interestingly, γδ and αβ T cells share the same progenitors, and they undergo a fate decision …
γδ T cell explorations seek terra firma
γδ T cell explorations seek terra firma | Nature Immunology Skip to main content Thank you
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[HTML][HTML] γδ T cells and their roles in immunotherapy: a narrative review
Y Chen, J Li, X Zeng, W Yuan, Y Xu - Annals of Blood, 2022 - aob.amegroups.org
Objective: In order to understand the activation mechanism of γδ T cells and their role in
tumor immunity and autoimmune diseases. Background: γδ T cells are a conserved …
tumor immunity and autoimmune diseases. Background: γδ T cells are a conserved …
γδ T cells in cancer
B Silva-Santos, K Serre, H Norell - Nature reviews immunology, 2015 - nature.com
With the promise of T cell-based therapy for cancer finally becoming reality, this Review
focuses on the less-studied γδ T cell lineage and its diverse responses to tumours. γδ T cells …
focuses on the less-studied γδ T cell lineage and its diverse responses to tumours. γδ T cells …