Abstract Purpose of Review The endocannabinoid (eCB) system, ie the receptors that
respond to the psychoactive component of cannabis, their endogenous ligands and the …

Purpose of review The purpose of the review was to revisit the possibility of the
endocannabinoid system being a therapeutic target for the treatment of obesity by focusing …

The endocannabinoid system (ECS) has emerged as one of the most relevant regulators of
energy balance. The ECS acts through two cannabinoid receptors: types 1 and 2 (CB1 and …

Endocannabinoid signalling is considered one of the most important modulatory systems in
a whole organism. Research has yielded great insight on the mechanisms that link …

The cannabinoid receptors for Δ 9-THC, and particularly, the CB 1 receptor, as well as its
endogenous ligands, the endocannabinoids anandamide and 2-arachidonoylglycerol, are …

Increasing evidence suggests that an overactive endocannabinoid system (ECS) may
contribute to the development of diabetes by promoting energy intake and storage, impairing …

The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …

Visceral obesity is a major risk factor for the development of insulin resistance which can
progress to overt type 2 diabetes (T2D) with loss of β‐cell function and, ultimately, loss of β …

Endocannabinoids and cannabinoid CB1 receptors are known to play a generalized role in
energy homeostasis. However, clinical trials with the first generation of CB1 blockers, now …

Endogenous signaling lipids (“endocannabinoids”) functionally related to Δ9-
tetrahydrocannabinol, the psychoactive ingredient of marijuana (Cannabis), are important …