Breast cancer remains the most common malignant cancer in women, with a staggering
incidence of two million cases annually worldwide; therefore, it is crucial to explore novel …

Cancer is defined by unrestrained cell proliferation due to impaired protein activity. Cell
cycle-related proteins are likely to play a role in human cancers, including proliferation …

NEK2 [NIMA (never in mitosis gene A)-related expressed kinase 2] is associated with
various biological behaviors in the development of cancer, while research concerning its …

NIMA-related kinase 7 (NEK7) is a serine/threonine kinase involved in cell cycle progression
via mitotic spindle formation and cytokinesis. It has been related to multiple cancers …

The family of human Nek (NIMA Related Kinase) kinases currently contains 11 members.
We have identified Nek8 as a new member of the Nek kinase family. For many of the Nek …

Background The NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that is involved
in regulation of centrosome duplication and spindle assembly during mitosis. Dysregulation …

Background The NEK serine/threonine protein kinases are involved in cell cycle
checkpoints, DNA damage repair, and apoptosis. Alterations in these pathways are …

Never in mitosis gene A (NIMA)-related kinase 2 (NEK2) is a microtubule-associated protein
that regulates spindle assembly in human cells and is overexpressed in various …

Abnormal expression and dysfunction of Never-in-mitosis-A-related kinase 2 (NEK2) result
in tumorigenesis. High levels of NEK2 are related to malignant progression, drug resistance …

We investigated the role of Nek2, a member of the serine‐threonine kinase family, in the
tumorigenic growth of breast carcinoma. Increased expression of Nek2 was observed in all …