Mammalian erythropoiesis involves chromatin condensation that is initiated in the early
stage of terminal differentiation. The mechanisms of chromatin condensation during …

Mammalian terminal erythropoiesis involves gradual but dramatic chromatin condensation
steps that are essential for cell differentiation. Chromatin and nuclear condensation is …

Mammalian terminal erythropoiesis involves several characteristic phenomena including
chromatin condensation and enucleation. One of the newly identified features of terminal …

A unique feature in mammalian erythropoiesis is the dramatic chromatin condensation
followed by enucleation. This step-by-step process starts at the beginning of terminal …

In all vertebrates, the cell nucleus becomes highly condensed and transcriptionally inactive
during the final stages of red cell biogenesis. Enucleation, the process by which the nucleus …

Enucleation, a rare feature of mammalian differentiation, occurs in 3 cell types: erythroblasts,
lens epithelium, and keratinocytes. Previous investigations suggest that caspase activation …

Terminal erythroid differentiation in vertebrates is characterized by progressive
heterochromatin formation and chromatin condensation and, in mammals, culminates in …

A characteristic feature of terminal erythropoiesis in mammals is extrusion of the highly
condensed nucleus out of the cytoplasm. Other vertebrates, including fish, reptiles …

Background Condensation of chromatin prior to enucleation is an essential component of
terminal erythroid maturation, and defects in this process are associated with inefficient …

Mammalian red blood cells lack nuclei. The molecular mechanisms underlying erythroblast
nuclear condensation and enucleation, however, remain poorly understood. Here we show …