[HTML][HTML] Sex differences in the diagnosis, treatment and prognosis of cancer: the rationale for an individualised approach

R Vera, O Juan-Vidal, MJ Safont-Aguilera… - Clinical and …, 2023 - Springer
Background Precision medicine in oncology aims to identify the most beneficial
interventions based on a patient's individual features and disease. However, disparities exist …

Sex disparities matter in cancer development and therapy

S Haupt, F Caramia, SL Klein, JB Rubin… - Nature Reviews …, 2021 - nature.com
Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …

[HTML][HTML] Investigation of sex and gender differences in oncology gains momentum: ESMO announces the launch of a Gender Medicine Task Force

BC Özdemir, S Oertelt-Prigione, AA Adjei… - Annals of …, 2022 - annalsofoncology.org
Important differences in cancer risk and survival between male and female patients have
been documented in the past few decades, with the latter having a reduced risk and better …

[HTML][HTML] Genome-wide sex and gender differences in cancer

CM Lopes-Ramos, J Quackenbush… - Frontiers in oncology, 2020 - frontiersin.org
Despite their known importance in clinical medicine, differences based on sex and gender
are among the least studied factors affecting cancer susceptibility, progression, survival, and …

[HTML][HTML] Sexual dimorphism in the incidence of human cancers

D Zheng, J Trynda, C Williams, JA Vold, JH Nguyen… - BMC cancer, 2019 - Springer
Background Sex differences in the incidences of cancers become a critical issue in both
cancer research and the development of precision medicine. However, details in these …

The gender perspective in cancer research and therapy: novel insights and on-going hypotheses

L Gabriele, M Buoncervello, B Ascione… - Annali Dell'istituto …, 2016 - annali.iss.it
Cancer represents a leading cause of death whose incidence is steadily increasing
worldwide due to the population aging. The Global Health Observatory of the World Health …

Cancer‐specific survival after diagnosis in men versus women: A pan‐cancer analysis

Y He, Y Su, J Zeng, W Chong, X Hu, Y Zhang… - MedComm, 2022 - Wiley Online Library
Comprehensive understanding of cancer‐specific survival differences in gender is critical for
cancer prevention and treatment. Based on the Surveillance Epidemiology and End Results …

[HTML][HTML] Treating sex and gender differences as a continuous variable can improve precision cancer treatments

W Yang, JB Rubin - Biology of sex Differences, 2024 - Springer
Background The significant sex and gender differences that exist in cancer mechanisms,
incidence, and survival, have yet to impact clinical practice. One barrier to translation is that …

[HTML][HTML] Comprehensive characterization of molecular differences in cancer between male and female patients

Y Yuan, L Liu, H Chen, Y Wang, Y Xu, H Mao, J Li… - Cancer cell, 2016 - cell.com
An individual's sex has been long recognized as a key factor affecting cancer incidence,
prognosis, and treatment responses. However, the molecular basis for sex disparities in …

Sex differences in cancer genomes: much learned, more unknown

C Zhu, PC Boutros - Endocrinology, 2021 - academic.oup.com
Cancer is a leading cause of death worldwide. Sex influences cancer in a bewildering
variety of ways. In some cancer types, it affects prevalence; in others, genomic profiles …