Advances in pathogenesis and therapeutic strategies for osteoporosis

S Song, Y Guo, Y Yang, D Fu - Pharmacology & therapeutics, 2022 - Elsevier
Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …

[HTML][HTML] Osteoporosis: Pathophysiology and therapeutic options

U Föger-Samwald, P Dovjak, U Azizi-Semrad… - EXCLI …, 2020 - ncbi.nlm.nih.gov
Osteoporosis is a metabolic bone disease that, on a cellular level, results from osteoclastic
bone resorption not compensated by osteoblastic bone formation. This causes bones to …

Advances in the occurrence and biotherapy of osteoporosis

Z Zou, W Liu, L Cao, Y Liu, T He… - Biochemical Society …, 2020 - portlandpress.com
Osteoporosis (OP) is a bone metabolic disease, is characterized by degeneration of bone
structure and decreased bone mass. It happens in more than 1/3 women and 1/5 men of …

The underlying pathophysiology and therapeutic approaches for osteoporosis

H Awasthi, D Mani, D Singh… - Medicinal research …, 2018 - Wiley Online Library
With an increase in the ageing population worldwide, the prevalence of osteoporosis
increases at an alarming rate in both male and female irrespective of their ethnicity. At …

[HTML][HTML] Interplay between inflammation and pathological bone resorption: insights into recent mechanisms and pathways in related diseases for future perspectives

MA Terkawi, G Matsumae, T Shimizu… - International Journal of …, 2022 - mdpi.com
Bone is a mineralized and elastic connective tissue that provides fundamental functions in
the human body, including mechanical support to the muscles and joints, protection of vital …

[HTML][HTML] Molecular mechanisms and emerging therapeutics for osteoporosis

JY Noh, Y Yang, H Jung - International journal of molecular sciences, 2020 - mdpi.com
Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

[PDF][PDF] Pharmacological agents and natural compounds: available treatments for osteoporosis.

M Martiniakova, M Babikova, R Omelka - Journal of Physiology & …, 2020 - jpp.krakow.pl
Osteoporosis, a systemic skeletal disease characterized by a decrease in bone mass and
deterioration of bone structure leading to an increased risk of fragility fractures, represents …

[HTML][HTML] Osteoporosis pathogenesis and treatment: existing and emerging avenues

B Liang, G Burley, S Lin, YC Shi - Cellular & Molecular Biology Letters, 2022 - Springer
Osteoporotic fractures lead to increased disability and mortality in the elderly population.
With the rapid increase in the aging population around the globe, more effective treatments …

[HTML][HTML] Gut microbiome and osteoporosis

K Ding, F Hua, W Ding - Aging and disease, 2020 - ncbi.nlm.nih.gov
Gut microbiome refers to the microbes that live in human digestive tract and are symbiotic
with the human body. They participate in the regulation of various physiological and …

[HTML][HTML] Cell death regulation: a new way for natural products to treat osteoporosis

Z Li, D Li, R Chen, S Gao, Z Xu, N Li - Pharmacological research, 2023 - Elsevier
Osteoporosis is a common metabolic bone disease that results from the imbalance of
homeostasis within the bone. Intra-bone homeostasis is dependent on a precise dynamic …