For many years, researchers have suggested that abnormalities in circadian rhythms may
underlie the development of mood disorders such as bipolar disorder (BPD), major …

Affective disorders such as major depression, bipolar disorder, and seasonal affective
disorder are associated with major disruptions in circadian rhythms. Indeed, altered …

This paper reviews some of the compelling evidence of disrupted circadian rhythms in
individuals with mood disorders (major depressive disorder, seasonal affective disorder, and …

Depression, particularly unipolar depression, has often been linked to circadian (ie
approximately 24-h) rhythm abnormalities. The observation that many diverse rhythms are …

In humans, most physiological and behavioural functions demonstrate a circadian
rhythmicity, which is essential to adequately cope with dramatic fluctuations occurring in the …

Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …

In humans almost all physiological and behavioural functions occur on a rhythmic basis.
Therefore the possibility that delays, advances or desynchronizations of circadian rhythms …

Circadian clocks are present in nearly all tissues of an organism, including the brain. The
brain is not only the site of the master coordinator of circadian rhythms located in the …

Most organisms (including humans) developed daily rhythms in almost every aspect of their
body. It is not surprising that rhythms are also related to affect in health and disease. In the …

The importance of time is ever prevalent in our world, and disruptions to the normal
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …