Novel diagnostic technologies and therapeutic approaches targeting chronic wound biofilms and microbiota

V Chen, JL Burgess, R Verpile, M Tomic-Canic… - Current dermatology …, 2022 - Springer
Abstract Purpose of Review To provide an up-to-date overview of recent developments in
diagnostic methods and therapeutic approaches for chronic wound biofilms and pathogenic …

Biofilms in chronic wounds: pathogenesis and diagnosis

YK Wu, NC Cheng, CM Cheng - Trends in biotechnology, 2019 - cell.com
Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

Biofilms and wounds: an identification algorithm and potential treatment options

SL Percival, C Vuotto, G Donelli… - Advances in wound care, 2015 - liebertpub.com
Significance: The presence of a “pathogenic” or “highly virulent” biofilm is a fundamental risk
factor that prevents a chronic wound from healing and increases the risk of the wound …

Detection of biofilm in wounds as an early indicator for risk for tissue infection and wound chronicity

KS Vyas, LK Wong - Annals of plastic surgery, 2016 - journals.lww.com
Wounds are dynamic environments in which dead tissue, exudate, and the bacterial
bioburden interact in a complex manner among themselves and with the tissue of the host …

Recent advances in non-conventional antimicrobial approaches for chronic wound biofilms: have we found the 'chink in the armor'?

S Kadam, S Shai, A Shahane, KS Kaushik - Biomedicines, 2019 - mdpi.com
Chronic wounds are a major healthcare burden, with huge public health and economic
impact. Microbial infections are the single most important cause of chronic, non-healing …

Biofilm-based wound care

R Wolcott, S Dowd, J Kennedy, C Jones - Adv Wound Care, 2010 - liebertpub.com
Background: Chronic infections produced by polymicrobial biofilms are responsible for the
majority of human infections. Biofilm has been demonstrated to infect most of the different …

Treatment options to manage wound biofilm

CE Jones, JP Kennedy - Advances in wound care, 2012 - liebertpub.com
Background: Bioburden is an accepted barrier to chronic wound healing. Defining the
significance, phenotype, clinical classification, and treatment guidelines has been …

Biofilms and their management: from concept to clinical reality

T Cowan - Journal of wound care, 2011 - magonlinelibrary.com
How can a better understanding of wound biofilms change your clinical practice? And what
is the likely impact on clinical outcomes? At this year's JWC lecture, sponsored by sorbion …

Development of a novel, highly quantitative in vivo model for the study of biofilm‐impaired cutaneous wound healing

AN Gurjala, MR Geringer, AK Seth… - Wound repair and …, 2011 - Wiley Online Library
ABSTRACT A growing body of evidence suggests that in addition to hypoxia, ischemia‐
reperfusion injury, and intrinsic host factors, bacterial biofilms represent a fourth major pillar …

Wound biofilm: current perspectives and strategies on biofilm disruption and treatments

RJ Snyder, G Bohn, J Hanft, L Harkless… - … : a compendium of …, 2017 - europepmc.org
The presence of bio lm remains a challenging factor that contributes to the delayed healing
of many chronic wounds. The major threat of chronic wound bio lms is their substantial …