Abstract Fibrous Dysplasia/McCune Albright syndrome (FD/MAS) represents a wide
spectrum of diseases due to somatic gain-of-function mutations of the GNAS gene. The …

Fibrous dysplasia (FD) is a non-malignant condition caused by post-zygotic, activating
mutations of the GNAS gene that results in inhibition of the differentiation and proliferation of …

Fibrous dysplasia/McCune-Albright syndrome (FD/MAS), the result of an early embryonic
postzygotic somatic activating pathogenic variant in GNAS (encoding the cAMP pathway …

Fibrous dysplasia (FD) is sometimes accompanied by extraskeletal manifestations that can
include any combination of café-au-lait macules, hyperfunctioning endocrinopathies, such …

Fibrous dysplasia is an uncommon mosaic disorder in which bone is replaced by structurally
unsound fibro-osseous tissue. It is caused by the sporadic post-zygotic activating mutations …

Abstract Fibrous dysplasia/McCune-Albright syndrome (FD/MAS) is a rare disorder of
striking complexity. It arises from somatic, gain-of-function mutations in GNAS, leading to …

GNAS mutations have been implicated in the development of fibrous dysplasia and multiple
endocrinopathies of the Albright-McCune syndrome. To investigate the diagnostic utility of …

Fibrous dysplasia (FD) is an uncommon and debilitating skeletal disorder resulting in
fractures, deformity, functional impairment, and pain. It arises from post-zygotic somatic …

Fibrous dysplasia (FD) is a rare bone disease caused by postzygotic somatic activating
mutations in the GNAS gene, which lead to constitutive activation of adenylyl cyclase and …

Fibrous dysplasia is a non‐neoplastic developmental process that affects the craniofacial
bones, characterized by painless enlargement as a result of bone substitution by abnormal …