Reactivity to laboratory stress provocation predicts relapse to cocaine
BACKGROUND: Cocaine dependence is a chronic relapsing disorder characterized by
periods of abstinence and high rates of return to drug using behavior. Elevated levels of …
periods of abstinence and high rates of return to drug using behavior. Elevated levels of …
Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes
R Sinha, M Garcia, P Paliwal, MJ Kreek… - Archives of general …, 2006 - jamanetwork.com
Background Cocaine dependence is associated with high rates of relapse. Stress and drug
cue exposure are known to increase cocaine craving and stress arousal, but the association …
cue exposure are known to increase cocaine craving and stress arousal, but the association …
Elevated cortisol and learning and memory deficits in cocaine dependent individuals: relationship to relapse outcomes
OBJECTIVE: Cocaine dependence is characterized by stress system dysregulation,
including elevated cortisol activity, emotional negativity, and behavioral disinhibition. High …
including elevated cortisol activity, emotional negativity, and behavioral disinhibition. High …
Stress in the daily lives of cocaine and heroin users: relationship to mood, craving, relapse triggers, and cocaine use
KL Preston, DH Epstein - Psychopharmacology, 2011 - Springer
Rationale Quantitative real-time data on the stress experienced by drug misusers in their
daily lives may provide additional insight into stress's role in drug use. Objective The …
daily lives may provide additional insight into stress's role in drug use. Objective The …
Psychosocial stress and the duration of cocaine use in non‐treatment seeking individuals with cocaine dependence
KH Karlsgodt, SE Lukas, I Elman - The American journal of drug …, 2003 - Taylor & Francis
The aim of this study was to explore a potential link between psychosocial stress and
cocaine dependence among 36 non–treatment‐seeking individuals enrolled in a brain …
cocaine dependence among 36 non–treatment‐seeking individuals enrolled in a brain …
[HTML][HTML] Enhanced sensitivity to stress and drug/alcohol craving in abstinent cocaine-dependent individuals compared to social drinkers
Chronic exposure to cocaine is associated with neuroadaptions in stress and reward circuits
that may increase susceptibility to relapse. We examined whether there are alterations in …
that may increase susceptibility to relapse. We examined whether there are alterations in …
Frequency of recent cocaine and alcohol use affects drug craving and associated responses to stress and drug-related cues
RATIONALE: Stress is known to increase drug craving, associated physiological arousal
and risk of relapse in drug dependent individuals. However, it is unclear whether these …
and risk of relapse in drug dependent individuals. However, it is unclear whether these …
Stress-induced craving and stress response in cocaine dependent individuals
R Sinha, D Catapano, S O'Malley - Psychopharmacology, 1999 - Springer
Two laboratory studies were conducted to examine the effects of acute psychological stress
on craving and stress reactivity in cocaine abusers. In the first preliminary study, we …
on craving and stress reactivity in cocaine abusers. In the first preliminary study, we …
Daily stressor sensitivity, abuse effects, and cocaine use in cocaine dependence
This study highlights respondent sensitivity to daily hassles as it relates to situational
cocaine use and perceived long-term effects of adverse events in childhood. Data were …
cocaine use and perceived long-term effects of adverse events in childhood. Data were …
Stressor-and corticotropin releasing factor-induced reinstatement and active stress-related behavioral responses are augmented following long-access cocaine self …
JR Mantsch, DA Baker, DM Francis, ES Katz… - …, 2008 - Springer
Rationale Stressful events during periods of drug abstinence likely contribute to relapse in
cocaine-dependent individuals. Excessive cocaine use may increase susceptibility to …
cocaine-dependent individuals. Excessive cocaine use may increase susceptibility to …