Objectives The use of doxorubicin, a drug utilised for many years to treat a wide variety of
cancers, has long been limited due to the significant toxicity that can occur not only during …

Doxorubicin (DOX) is a chemotherapeutic agent frequently used for the treatment of a variety
of tumor types, such as breast cancer. Despite the long history of DOX, the mechanistic …

Anthracycline antibiotic doxorubicin (DOX) belongs among the most important
antineoplastics used in cancer therapy. Unfortunately, its cytostatic effect in therapeutic …

The cytostatic drug doxorubicin is a well-known chemotherapeutic agent which is used in
treatment of a wide variety of cancers. A key factor in the response of cancer cells to …

The role of metabolism in daunorubicin (DAUN)-and doxorubicin (DOX)-associated toxicity
in cancer patients is dependent on whether the parent drugs or major metabolites …

Objectives The frontline drug doxorubicin has been used for treating cancer for over 30
years. While providing a cure in select cases, doxorubicin causes toxicity to most major …

Doxorubicin or Adriamycin, is one of the most widely used chemotherapeutic drug for
treating a myriad of cancers. It induces cell death through multiple intracellular targets …

Cancer remains one of the highest leading causes of morbidity and mortality worldwide.
Anthracyclines, specifically Doxorubicin (DOX), have been used for the past three decades …

Anthracycline cardiotoxicity remains a serious problem in paediatric and adult cancer
survivors, and the advancement of cardio-oncology is a necessary step for an effective care …

Doxorubicin is an extensively used anti-neoplastic drug used for solid and hematogenous
cancer since the 1950s, and its usage is limited due to its toxic effects upon various organs …