The corpus luteum (CL) plays a vital role in regulating the reproductive cycle, fertility, and in
maintaining pregnancy. Interferon-tau (IFNT) is the maternal recognition of a pregnancy …

Interferon-tau (IFNT), a maternal recognition of pregnancy (MRP) signals in domestic
ruminants, suppresses the release of luteolytic pulses of uterine prostaglandin F2a (PGF2a) …

Understanding luteal maintenance during early pregnancy is of substantial biological and
practical importance. Characterizing effects of early pregnancy, however, has historically …

This review examines the function of the corpus luteum (CL) with emphasis on pregnancy in
ruminant models and the possible impact of pregnancy in conferring luteal resistance to …

Background Maintenance of the corpus luteum (CL) beyond the time of luteolysis is
essential for establishing pregnancy. Identifying the distinct features of early pregnancy CL …

Interferon tau (IFN-τ) is the pregnancy recognition signal secreted by the trophectodermal
cells of the developing bovine embryo that prevents luteolysis and maintains critical …

This manuscript reviews the mechanisms that maintain the corpus luteum (CL) of pregnancy
in ruminants. In mammals, ovulation and luteinization of the remaining cells in the CL are …

Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during
early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects …

This review focuses on the paracrine and endocrine actions of interferon tau (IFNT) during
pregnancy recognition and establishment in ruminants. Pregnancy recognition involves the …

Since the discovery of interferon-tau (IFNT) over 30 years ago as the trophectodermal
cytokine responsible for the maintenance of the maternal corpus luteum (CL) in ruminants …