[HTML][HTML] Synthesis and greener pastures biological study of bis-thiadiazoles as potential Covid-19 drug candidates
A novel series of bis-(Abdelhamid et al., 2017, Banerjee et al., 2018, Bharanidharan et al.,
2022) thiadiazoles was synthesized from the reaction of precursor dimethyl 2, 2′-(1, 2 …
2022) thiadiazoles was synthesized from the reaction of precursor dimethyl 2, 2′-(1, 2 …
[PDF][PDF] Synthesis and identification of novel potential thiadiazole based molecules containing 1, 2, 3-triazole moiety against COVID-19 main protease through structure …
HRM Rashdan, AH Abdelmonsef… - Appl. Biochem …, 2021 - researchgate.net
In the present study, 1-(5-Methyl-1-(5-(methylthio)-1, 3, 4-thiadiazol-2-yl)-1H-1, 2, 3-triazol-4-
yl) ethan-1-one 2 was used as predecessor molecule for synthesis of methyl 2-(1-(5-methyl …
yl) ethan-1-one 2 was used as predecessor molecule for synthesis of methyl 2-(1-(5-methyl …
[HTML][HTML] Potential COVID-19 drug candidates based on diazinyl-thiazol-imine moieties: synthesis and greener pastures biological study
A novel series of 1-aryl-N-[4-phenyl-5-(arylazo) thiazol-2-yl) methanimines has been
synthesized via the condensation of 2-amino-4-phenyl-5-arylazothiazole with various …
synthesized via the condensation of 2-amino-4-phenyl-5-arylazothiazole with various …
[HTML][HTML] In silico study to identify novel potential thiadiazole-based molecules as anti-Covid-19 candidates by hierarchical virtual screening and molecular dynamics …
HRM Rashdan, AH Abdelmonsef - Structural Chemistry, 2022 - Springer
In the present study, a new category of 1, 3, 4-thiadiazoles was developed by submitting
methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate to react with the …
methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate to react with the …
Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi …
J Haribabu, V Garisetti, RE Malekshah… - Journal of molecular …, 2022 - Elsevier
Abstract Two heterocyclic azole compounds, 3-(2, 3-dihydrobenzo [d] thiazol-2-yl)-4H-
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …
Activity profiling of natural and synthetic SARS-Cov-2 inhibitors using molecular docking analysis
EC Ohaekenyem, CT Onyema… - Pure and Applied …, 2024 - degruyter.com
COVID-19, the global pandemic caused by SARS-Corona virus 2 (SARS-CoV-2), recently
ravaged the World with various efforts charged towards finding therapeutic drug targets for …
ravaged the World with various efforts charged towards finding therapeutic drug targets for …
[HTML][HTML] New thiazol-pyridazine derivatives as antimicrobial and antiviral candidates: Synthesis, and application
In this manuscript, we are motivated to investigate the reaction site-selectivity for the hydrazo
thiazole derivatives (6a–c) with different types of active methylene groups such as …
thiazole derivatives (6a–c) with different types of active methylene groups such as …
Synthesis of novel 2, 5-bis (substituted thio)-1, 3, 4-thiadiazoles by acid catalyzed intermolecular cyclization reactions of substituted dithiocarbazates as a possible …
A convenient and facile synthesis of a privileged pharmaceutical scaffolds, 2, 5-bis
(substituted thio)-1, 3, 4-thiadiazoles is accomplished. The reaction of hydrazine hydrate …
(substituted thio)-1, 3, 4-thiadiazoles is accomplished. The reaction of hydrazine hydrate …
[HTML][HTML] Repurposing benzimidazole and benzothiazole derivatives as potential inhibitors of SARS-CoV-2: DFT, QSAR, molecular docking, molecular dynamics …
Abstract Density Functional Theory (DFT) and Quantitative Structure-Activity Relationship
(QSAR) studies were performed on four benzimidazoles (compounds 1–4) and two …
(QSAR) studies were performed on four benzimidazoles (compounds 1–4) and two …
Identification of 1, 2, 3-triazole-phthalimide derivatives as potential drugs against COVID-19: a virtual screening, docking and molecular dynamic study
VN Holanda, EMA Lima, WV Silva… - Journal of …, 2022 - Taylor & Francis
In this work we aimed to perform an in silico predictive screening, docking and molecular
dynamic study to identify 1, 2, 3-triazole-phthalimide derivatives as drug candidates against …
dynamic study to identify 1, 2, 3-triazole-phthalimide derivatives as drug candidates against …