The clinical characterization of the adult patient with depression aimed at personalization of management
Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …
characterize the individual patient who has received this diagnosis in order to personalize …
Personalized medicine for depression: can we match patients with treatments?
Objective: Response to specific depression treatments varies widely among individuals.
Understanding and predicting that variation could have great benefits for people living with …
Understanding and predicting that variation could have great benefits for people living with …
Personalized treatment of adult depression: medication, psychotherapy, or both? A systematic review
Background Personalized medicine aims to identify which characteristics of an individual
predict the outcome of a specific treatment, in order to get a better match between the …
predict the outcome of a specific treatment, in order to get a better match between the …
[HTML][HTML] Optimizing personalized management of depression: the importance of real‐world contexts and the need for a new convergence paradigm in mental health
CF Reynolds - World Psychiatry, 2020 - ncbi.nlm.nih.gov
In this issue of the journal, Maj et al1 have revisited a fundamental tenet of psychiatric
medicine, namely, that more precise clinical characterization of patients with depression will …
medicine, namely, that more precise clinical characterization of patients with depression will …
The clinical effectiveness of using a predictive algorithm to guide antidepressant treatment in primary care (PReDicT): an open-label, randomised controlled trial
M Browning, AC Bilderbeck, R Dias… - …, 2021 - nature.com
Depressed patients often do not respond to the first antidepressant prescribed, resulting in
sequential trials of different medications. Personalised medicine offers a means of reducing …
sequential trials of different medications. Personalised medicine offers a means of reducing …
Abandoning personalization to get to precision in the pharmacotherapy of depression
RH Perlis - World Psychiatry, 2016 - Wiley Online Library
Effectiveness studies and analyses of naturalistic cohorts demonstrate that many patients
with major depressive disorder do not experience symptomatic remission with …
with major depressive disorder do not experience symptomatic remission with …
Predicting treatment outcome in depression: an introduction into current concepts and challenges
Improving response and remission rates in major depressive disorder (MDD) remains an
important challenge. Matching patients to the treatment they will most likely respond to …
important challenge. Matching patients to the treatment they will most likely respond to …
Personalized psychotherapy for adult depression: a meta-analytic review
Personalized medicine is aimed at identifying which characteristics of an individual predict
the outcome of a specific treatment, in order to get a better match between the individual and …
the outcome of a specific treatment, in order to get a better match between the individual and …
Psychotherapies for depression: a network meta‐analysis covering efficacy, acceptability and long‐term outcomes of all main treatment types
P Cuijpers, S Quero, H Noma, M Ciharova… - World …, 2021 - Wiley Online Library
The effects of psychotherapies for depression have been examined in several hundreds of
randomized trials, but no recent network meta‐analysis (NMA) has integrated the results of …
randomized trials, but no recent network meta‐analysis (NMA) has integrated the results of …
The symptom‐specific efficacy of antidepressant medication vs. cognitive behavioral therapy in the treatment of depression: Results from an individual patient data …
L Boschloo, E Bekhuis, ES Weitz, M Reijnders… - World …, 2019 - Wiley Online Library
A recent individual patient data meta‐analysis showed that antidepressant medication is
slightly more efficacious than cognitive behavioral therapy (CBT) in reducing overall …
slightly more efficacious than cognitive behavioral therapy (CBT) in reducing overall …