Colorectal cancer (CRC) is one of the most common and deadly malignancies in the world.
Most CRCs are initiated by aberrant activation of the Wnt/ß-catenin signaling pathway …

Colorectal cancer (CRC), the third most frequent occurred cancer, is associated with high
mortality and extremely poor prognosis. Ginsenoside Rg3 (Rg3), one of the …

Colorectal cancer (CRC) is among the most common malignant diseases with high morbidity
and mortality rates. Ginseng and its major extracts, ginsenosides, have been used in …

Anti-angiogenic therapy has been successfully applied to treat colorectal cancer (CRC).
Ginsenoside Rg3, derived from the Chinese herb ginseng, has anti-vascularization effects …

Background Treating colorectal cancer (CRC) continues to be a clinical challenge. Studies
have shown that epithelial-mesenchymal transition (EMT) is a critical step in tumor …

Chemotherapy is one of the most commonly used treatments for patients with advanced
colon cancer, yet the toxicity of chemotherapy agents, such as 5‑fluorouracil (5‑FU), limits …

American ginseng (Panax quinquefolius L., Araliaceae) possesses anti-cancer potential and
is one of the most commonly used herbal medicines in the United States. Ginsenoside Rg3 …

Compound K (20-O-beta-d-glucopyranosyl-20 (S)-protopanaxadiol, CK), an intestinal
bacterial metabolite of ginseng protopanaxadiol saponins, has been shown to inhibit cell …

Ginsenoside Rg3, the main constituent isolated from Panax ginseng, has been of interest for
use as a cancer preventive or therapeutic agent. We investigated here whether Rg3 can …

Ginsenoside compound K (CK) is an intestinal microbiota metabolite of ginsenoside Rb1, a
major constituent in American ginseng. However, previous ginseng anti-cancer observations …