Drug delivery strategies for antibiofilm therapy
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …
biofilms, their widespread clinical use is hindered by poor biocompatibility and …
New antibiotic agents and approaches to treat biofilm-associated infections
AS Lynch, D Abbanat - Expert opinion on therapeutic patents, 2010 - Taylor & Francis
Importance of the field: Current antibiotics have classically been developed to treat
infections involving planktonic bacterial populations in acute infection settings and are …
infections involving planktonic bacterial populations in acute infection settings and are …
Drug delivery approaches for enhanced antibiofilm therapy
T Wang, EJ Cornel, C Li, J Du - Journal of Controlled Release, 2023 - Elsevier
Biofilms have attracted increasing attention in recent years. Many bacterial infections are
associated with biofilm formation. A bacterial biofilm is an aggregated membrane-like …
associated with biofilm formation. A bacterial biofilm is an aggregated membrane-like …
[HTML][HTML] Prospects for anti-biofilm pharmaceuticals
PS Stewart - Pharmaceuticals, 2015 - mdpi.com
This commentary highlights several avenues currently being pursued in research labs to the
development of new anti-biofilm pharmaceuticals. There is a real need for alternative …
development of new anti-biofilm pharmaceuticals. There is a real need for alternative …
[HTML][HTML] Targeting biofilms therapy: current research strategies and development hurdles
Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
Novel approaches to combat bacterial biofilms
Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …
[HTML][HTML] Combating bacterial biofilms: current and emerging antibiofilm strategies for treating persistent infections
AG Abdelhamid, AE Yousef - Antibiotics, 2023 - mdpi.com
Biofilms are intricate multicellular structures created by microorganisms on living (biotic) or
nonliving (abiotic) surfaces. Medically, biofilms often lead to persistent infections, increased …
nonliving (abiotic) surfaces. Medically, biofilms often lead to persistent infections, increased …
Strategies for antimicrobial drug delivery to biofilm
C Martin, W LiLow, A Gupta… - Current …, 2015 - ingentaconnect.com
Biofilms are formed by the attachment of single or mixed microbial communities to a variety
of biological and/or synthetic surfaces. Biofilm micro-organisms benefit from many …
of biological and/or synthetic surfaces. Biofilm micro-organisms benefit from many …
Beyond conventional antibiotics—New directions for combination products to combat biofilm
DF Bayramov, JA Neff - Advanced drug delivery reviews, 2017 - Elsevier
Medical device related infections are a significant and growing source of morbidity and
mortality. Biofilm formation is a common feature of medical device infections that is not …
mortality. Biofilm formation is a common feature of medical device infections that is not …
Agents that inhibit bacterial biofilm formation
N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …
a biofilm can also survive harsh conditions and withstand the host's immune system …