[HTML][HTML] Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides
Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …
switch alters host-microbe interactions and is critical for pathogenicity. However, in …
A novel resistance pathway for calcineurin inhibitors in the human-pathogenic mucorales Mucor circinelloides
S Vellanki, RB Billmyre, A Lorenzen, M Campbell… - MBio, 2020 - Am Soc Microbiol
Mucormycosis is an emerging lethal fungal infection in immunocompromised patients.
Mucor circinelloides is a causal agent of mucormycosis and serves as a model system to …
Mucor circinelloides is a causal agent of mucormycosis and serves as a model system to …
Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides
Calcineurin plays essential roles in virulence and growth of pathogenic fungi and is a target
of the natural products FK 506 and C yclosporine A. In the pathogenic mucoralean fungus M …
of the natural products FK 506 and C yclosporine A. In the pathogenic mucoralean fungus M …
Rapamycin Exerts Antifungal Activity In Vitro and In Vivo against Mucor circinelloides via FKBP12-Dependent Inhibition of Tor
The zygomycete Mucor circinelloides is an opportunistic fungal pathogen that commonly
infects patients with malignancies, diabetes mellitus, and solid organ transplants. Despite …
infects patients with malignancies, diabetes mellitus, and solid organ transplants. Despite …
[HTML][HTML] RNAi-based functional genomics identifies new virulence determinants in mucormycosis
Mucorales are an emerging group of human pathogens that are responsible for the lethal
disease mucormycosis. Unfortunately, functional studies on the genetic factors behind the …
disease mucormycosis. Unfortunately, functional studies on the genetic factors behind the …
Drug-resistant epimutants exhibit organ-specific stability and induction during murine infections caused by the human fungal pathogen Mucor circinelloides
Z Chang, J Heitman - MBio, 2019 - Am Soc Microbiol
The environmentally ubiquitous fungus Mucor circinelloides is a primary cause of the
emerging disease mucormycosis. Mucor infection is notable for causing high morbidity and …
emerging disease mucormycosis. Mucor infection is notable for causing high morbidity and …
Identification and analysis of genes involved in the control of dimorphism in Mucor circinelloides (syn. racemosus)
AM Wolff, KF Appel, JB Petersen, U Poulsen… - FEMS yeast …, 2002 - academic.oup.com
Mucor circinelloides (syn. racemosus) is a non-pathogenic dimorphic fungus belonging to
the class of zygomycetes. We are developing a novel system for heterologous protein …
the class of zygomycetes. We are developing a novel system for heterologous protein …
[HTML][HTML] Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides
Mucormycosis—an emergent, deadly fungal infection—is difficult to treat, in part because the
causative species demonstrate broad clinical antifungal resistance. However, the …
causative species demonstrate broad clinical antifungal resistance. However, the …
[HTML][HTML] Sporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides
CH Li, M Cervantes, DJ Springer, T Boekhout… - PLoS …, 2011 - journals.plos.org
Mucor circinelloides is a zygomycete fungus and an emerging opportunistic pathogen in
immunocompromised patients, especially transplant recipients and in some cases otherwise …
immunocompromised patients, especially transplant recipients and in some cases otherwise …
[HTML][HTML] Components of a new gene family of ferroxidases involved in virulence are functionally specialized in fungal dimorphism
Mucormycosis is an emerging angio-invasive infection caused by Mucorales that presents
unacceptable mortality rates. Iron uptake has been related to mucormycosis, since serum …
unacceptable mortality rates. Iron uptake has been related to mucormycosis, since serum …
相关搜索
- dimorphic transitions pathogen interactions
- mucor circinelloides size dimorphism
- mucor circinelloides germination pathway
- mucor circinelloides analysis of genes
- mucor circinelloides murine infections
- dimorphic transitions drug responses
- mucor circinelloides control of dimorphism
- mucor circinelloides identification and analysis