Tissue engineering has yet to reach its ideal goal, ie. creating profitable off-the-shelf tissues
and organs, designing scaffolds and three-dimensional tissue architectures that can …

Studying aging, as a physiological process that can cause various pathological phenotypes,
has attracted lots of attention due to its increasing burden and prevalence. Therefore …

Nowadays, it is clear that adult stem cells, also called as tissue stem cells, play a central role
to repair and maintain the tissue in which they reside by their self-renewal ability and …

Stem cells persist throughout life, replacing cells lost to homeostatic turnover, injury, and
disease. However, their functions decline with age, which contributes to degeneration and …

Although aging is a physiological process, it has raised interest in the science of aging and
rejuvenation because of the increasing burden on the rapidly aging global population. With …

Most adult organs contain regenerative stem cells, often organized in specific niches. Stem
cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on …

Characterized by dysfunction of tissues, organs, organ systems and the whole organism,
aging results from the reduced function of effective stem cell populations. Recent advances …

Aging is considered as inevitable changes at different levels of genome, cell, and organism.
From the accumulation of DNA damages to imperfect protein homeostasis, altered cellular …

Stem cells are a promising source for regenerative medicine to cure a plethora of diseases
that are currently treated based on either palliative or symptomatic relief or by preventing …

There is a critical shortage of organs available for donation to patients suffering from
degenerative diseases of various organ systems. This shortage becomes more severe …