Melatonin and its atheroprotective effects: a review

G Favero, LF Rodella, RJ Reiter, R Rezzani - Molecular and cellular …, 2014 - Elsevier
Atherosclerosis is a chronic vascular disease in which oxidative stress and inflammation are
commonly implicated as major causative factors. Identification of novel strategies that …

Melatonin in cardiovascular disease

A Dominguez-Rodriguez - Expert Opinion on Investigational Drugs, 2012 - Taylor & Francis
This editorial refers to “Cardiovascular effects of melatonin receptor agonists”. The hormone
melatonin is synthesized primarily in the pineal gland, retina, several peripheral tissues and …

[PDF][PDF] Relationship between melatonin and cardiovascular disease

F Ozkalayci, U Kocabas, BU Altun, S Pandi-Perumal… - Cureus, 2021 - cureus.com
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality
worldwide. The coronary atherosclerotic process involves different pathological …

[HTML][HTML] Evidence for the benefits of melatonin in cardiovascular disease

M Tobeiha, A Jafari, S Fadaei, SMA Mirazimi… - Frontiers in …, 2022 - frontiersin.org
The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …

Role of melatonin in the angiogenesis potential; highlights on the cardiovascular disease

A Rahbarghazi, M Siahkouhian, R Rahbarghazi… - Journal of …, 2021 - Springer
Melatonin possesses multi-organ and pleiotropic effects with potency to control
angiogenesis at both molecular and cellular levels. To date, many efforts have been made to …

Cardiovascular diseases: protective effects of melatonin

S Tengattini, RJ Reiter, DX Tan… - Journal of pineal …, 2008 - Wiley Online Library
This brief review considers some of the cardiac diseases and conditions where free radicals
and related reactants are believed to be causative. The report also describes the beneficial …

[HTML][HTML] The mystery behind the pineal gland: melatonin affects the metabolism of cholesterol

K Karolczak, C Watala - Oxidative Medicine and Cellular Longevity, 2019 - hindawi.com
Melatonin may be considered a cardioprotective agent. Since atherogenesis is partly
associated with the metabolism of lipoproteins, it seems plausible that melatonin affects …

Clinical application of melatonin in the treatment of cardiovascular diseases: current evidence and new insights into the cardioprotective and cardiotherapeutic …

MH Pourhanifeh, E Dehdashtian… - … Drugs and Therapy, 2022 - Springer
Cardiovascular diseases (CVDs) are the leading global cause of mortality and disability,
tending to happen in younger individuals in developed countries. Despite improvements in …

[HTML][HTML] Melatonin as a therapeutic agent for alleviating endothelial dysfunction in cardiovascular diseases: Emphasis on oxidative stress

X Zhang, Y Zheng, Z Wang, J Gan, B Yu, B Lu… - Biomedicine & …, 2023 - Elsevier
The vascular endothelium is vital in maintaining cardiovascular health by regulating
vascular permeability and tone, preventing thrombosis, and controlling vascular …

Effects of melatonin on cardiovascular risk factors and metabolic syndrome: a comprehensive review

M Imenshahidi, G Karimi, H Hosseinzadeh - … -Schmiedeberg's Archives of …, 2020 - Springer
Melatonin, as a neuroendocrine hormone, is produced primarily by the pineal gland.
Melatonin, a pleotropic molecule, acts as a free radical scavenger, antioxidant, and regulator …