DNA vaccines have inherent advantages compared to other vaccine types, including safety,
rapid design and construction, ease and speed to manufacture, and thermostability …

Recently newer synthetic DNA vaccines have been rapidly advanced to clinical study and
have demonstrated an impressive degree of immune potency and tolerability. Improvements …

A number of noteworthy technology advances in DNA vaccines research and development
over the past few years have led to the resurgence of this field as a viable vaccine modality …

Immunogenicity of DNA vaccines varies significantly due to many factors including the
inherent immunogenicity of the protein antigen encoded in the DNA vaccine, the optimal …

The naked delivery of nucleic acid vaccines is notoriously inefficient, and an enabling
delivery technology is required to direct efficiently these constructs intracellularly. A delivery …

Vaccination is historically one of the most important methods for preventing infectious
diseases in humans and animals. Due to recent advances in understanding the biology of …

DNA vaccines are ideal candidates for global vaccination purposes because they are
inexpensive and easy to manufacture on a large scale such that even people living in low …

DNA immunization is an attractive technology owing to its potential to induce balanced and
long-lived immune responses. However, progress into the clinic has been hampered by the …

Electroporation (EP) of either muscle or skin has proven to be an efficient method for
increasing DNA-based vaccine delivery and immunogenicity in small and large animals …

In recent years, DNA vaccines have undergone a number of technological advancements
that have incited renewed interest and heightened promise in the field. Two such …